Synergistic toxicity in an in vivo model of neurodegeneration through the co-expression of human TDP-43(M337V) and tau(T175D) protein

Although it has been suggested that the co-expression of multiple pathological proteins associated with neurodegeneration may act synergistically to induce more widespread neuropathology, experimental evidence of this is sparse. We have previously shown that the expression of Thr(175)Asp-tau (tau(T1...

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Detalles Bibliográficos
Autores principales: Moszczynski, Alexander J., Harvey, Madeline, Fulcher, Niveen, de Oliveira, Cleusa, McCunn, Patrick, Donison, Neil, Bartha, Robert, Schmid, Susanne, Strong, Michael J., Volkening, Kathryn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839082/
https://www.ncbi.nlm.nih.gov/pubmed/31703746
http://dx.doi.org/10.1186/s40478-019-0816-1

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