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Antibiotic-modulated microbiome suppresses lethal inflammation and prolongs lifespan in Treg-deficient mice

BACKGROUND: Regulatory T cell (Treg) deficiency leads to IPEX syndrome, a lethal autoimmune disease, in Human and mice. Dysbiosis of the gut microbiota in Treg-deficient scurfy (SF) mice has been described, but to date, the role of the gut microbiota remains to be determined. RESULTS: To examine how...

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Detalles Bibliográficos
Autores principales:	He, Baokun, Liu, Yuying, Hoang, Thomas K., Tian, Xiangjun, Taylor, Christopher M., Luo, Meng, Tran, Dat Q., Tatevian, Nina, Rhoads, J. Marc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839243/ https://www.ncbi.nlm.nih.gov/pubmed/31699146 http://dx.doi.org/10.1186/s40168-019-0751-1

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