Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling

BACKGROUND: Excessive TGF-β signalling has been shown to underlie pulmonary hypertension (PAH). Human pulmonary artery smooth muscle cells (HPASMCs) can release extracellular vesicles (EVs) but their contents and significance have not yet been studied. Here, we aimed to analyse the contents and biol...

Descripción completa

Detalles Bibliográficos
Autores principales: de la Cuesta, Fernando, Passalacqua, Ilaria, Rodor, Julie, Bhushan, Raghu, Denby, Laura, Baker, Andrew H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839246/
https://www.ncbi.nlm.nih.gov/pubmed/31703702
http://dx.doi.org/10.1186/s12964-019-0449-9

Ejemplares similares

Ejemplares similares