Multiple Neurologic Deficits and Cognitive Decline in a Young Woman

We present the clinicopathologic conference of a 34-year-old lady with history of facial palsy 14 years ago who developed new deficits of mononeuritis multiplex, maculopapular rash, pancytopenia, splenomegaly, lung involvement and cognitive decline rapidly over three years. Investigations revealed p...

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Autores principales: Elavarasi, Arunmozhimaran, George, Jacob, Sharma, Mehar Chand, Kumari, Kalpana, Garg, Ajay, Pandit, Awadh Kishor, Satapathy, Abhishek, Goyal, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Clinicopathological Conference
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839316/
https://www.ncbi.nlm.nih.gov/pubmed/31736585
http://dx.doi.org/10.4103/aian.AIAN_293_19
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author Elavarasi, Arunmozhimaran
George, Jacob
Sharma, Mehar Chand
Kumari, Kalpana
Garg, Ajay
Pandit, Awadh Kishor
Satapathy, Abhishek
Goyal, Vinay
author_facet Elavarasi, Arunmozhimaran
George, Jacob
Sharma, Mehar Chand
Kumari, Kalpana
Garg, Ajay
Pandit, Awadh Kishor
Satapathy, Abhishek
Goyal, Vinay
author_sort Elavarasi, Arunmozhimaran
collection PubMed
description We present the clinicopathologic conference of a 34-year-old lady with history of facial palsy 14 years ago who developed new deficits of mononeuritis multiplex, maculopapular rash, pancytopenia, splenomegaly, lung involvement and cognitive decline rapidly over three years. Investigations revealed pancytopenia, reversal of albumin globulin ratio, mediastinal adenopathy, ANA positivity, low C3 levels with the CSF being inflammatory and MRI showing extensive hemorrhagic lesions with mass effect. She had a rapidly progressive fatal course over three years with the disease being undiagnosed. This case was presented in the annual meeting of the Indian Academy of Neurology in September 2018.
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spelling pubmed-68393162019-11-15 Multiple Neurologic Deficits and Cognitive Decline in a Young Woman Elavarasi, Arunmozhimaran George, Jacob Sharma, Mehar Chand Kumari, Kalpana Garg, Ajay Pandit, Awadh Kishor Satapathy, Abhishek Goyal, Vinay Ann Indian Acad Neurol Clinicopathological Conference We present the clinicopathologic conference of a 34-year-old lady with history of facial palsy 14 years ago who developed new deficits of mononeuritis multiplex, maculopapular rash, pancytopenia, splenomegaly, lung involvement and cognitive decline rapidly over three years. Investigations revealed pancytopenia, reversal of albumin globulin ratio, mediastinal adenopathy, ANA positivity, low C3 levels with the CSF being inflammatory and MRI showing extensive hemorrhagic lesions with mass effect. She had a rapidly progressive fatal course over three years with the disease being undiagnosed. This case was presented in the annual meeting of the Indian Academy of Neurology in September 2018. Wolters Kluwer - Medknow 2019 2019-10-25 /pmc/articles/PMC6839316/ /pubmed/31736585 http://dx.doi.org/10.4103/aian.AIAN_293_19 Text en Copyright: © 2006 - 2019 Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Clinicopathological Conference
Elavarasi, Arunmozhimaran
George, Jacob
Sharma, Mehar Chand
Kumari, Kalpana
Garg, Ajay
Pandit, Awadh Kishor
Satapathy, Abhishek
Goyal, Vinay
Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title_full Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title_fullStr Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title_full_unstemmed Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title_short Multiple Neurologic Deficits and Cognitive Decline in a Young Woman
title_sort multiple neurologic deficits and cognitive decline in a young woman
topic Clinicopathological Conference
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839316/
https://www.ncbi.nlm.nih.gov/pubmed/31736585
http://dx.doi.org/10.4103/aian.AIAN_293_19
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