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Possible Role of Amyloid Cross-Seeding in Evolvability and Neurodegenerative Disease
Aging-related neurodegenerative disorders are frequently associated with the aggregation of multiple amyloidogenic proteins (APs), although the reason why such detrimental phenomena have emerged in the post-reproductive human brain across evolution is unclear. Speculatively, APs might provide physio...
Autores principales: | Hashimoto, Makoto, Ho, Gilbert, Takamatsu, Yoshiki, Wada, Ryoko, Sugama, Shuei, Takenouchi, Takato, Waragai, Masaaki, Masliah, Eliezer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839461/ https://www.ncbi.nlm.nih.gov/pubmed/31524179 http://dx.doi.org/10.3233/JPD-191675 |
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