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Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples
Human cysteine cathepsins constitute an 11-membered family of proteases responsible for degradation of proteins in cellular endosomal–lysosomal compartments as such, they play important roles in antigen processing, cellular stress signaling, autophagy, and senescence. Moreover, for many years these...
Autores principales: | Poreba, Marcin, Groborz, Katarzyna, Vizovisek, Matej, Maruggi, Marco, Turk, Dusan, Turk, Boris, Powis, Garth, Drag, Marcin, Salvesen, Guy S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839509/ https://www.ncbi.nlm.nih.gov/pubmed/31803426 http://dx.doi.org/10.1039/c9sc00997c |
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