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Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples

Human cysteine cathepsins constitute an 11-membered family of proteases responsible for degradation of proteins in cellular endosomal–lysosomal compartments as such, they play important roles in antigen processing, cellular stress signaling, autophagy, and senescence. Moreover, for many years these...

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Detalles Bibliográficos
Autores principales: Poreba, Marcin, Groborz, Katarzyna, Vizovisek, Matej, Maruggi, Marco, Turk, Dusan, Turk, Boris, Powis, Garth, Drag, Marcin, Salvesen, Guy S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839509/
https://www.ncbi.nlm.nih.gov/pubmed/31803426
http://dx.doi.org/10.1039/c9sc00997c

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