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Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification

Helicates and related metallofoldamers, synthesised by dynamic self-assembly, represent an area of chemical space inaccessible by traditional organic synthesis, and yet with potential for discovery of new classes of drug. Here we report that water-soluble, optically pure Fe(ii)- and even Zn(ii)-base...

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Detalles Bibliográficos
Autores principales:	Song, Hualong, Rogers, Nicola J., Allison, Simon J., Brabec, Viktor, Bridgewater, Hannah, Kostrhunova, Hana, Markova, Lenka, Phillips, Roger M., Pinder, Emma C., Shepherd, Samantha L., Young, Lawrence S., Zajac, Juraj, Scott, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839601/ https://www.ncbi.nlm.nih.gov/pubmed/31803429 http://dx.doi.org/10.1039/c9sc02651g

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