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Periodic Oxaliplatin Administration in Synergy with PER2‐Mediated PCNA Transcription Repression Promotes Chronochemotherapeutic Efficacy of OSCC
Developing chemotherapeutic resistance affects clinical outcomes of oxaliplatin treatment on various types of cancer. Thus, it is imperative to explore alternative therapeutic strategies to improve the efficacy of oxaliplatin. Here, it is shown that circadian regulator period 2 (PER2) can potentiate...
Autores principales: | Tang, Qingming, Xie, Mengru, Yu, Shaoling, Zhou, Xin, Xie, Yanling, Chen, Guangjin, Guo, Fengyuan, Chen, Lili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839751/ https://www.ncbi.nlm.nih.gov/pubmed/31728273 http://dx.doi.org/10.1002/advs.201900667 |
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