Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation

BACKGROUND AND AIM: Autophagy is an essential process involved in the pathogenesis of inflammatory bowel disease (IBD). Although there are many data showing the roles of autophagy in intestinal epithelial cells (IECs), the mechanisms involved remain to be fully elucidated. We investigated the influe...

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Detalles Bibliográficos
Autores principales: Kubota, Minori, Kakimoto, Kazuki, Nakagawa, Takatoshi, Koubayashi, Eiko, Nakazawa, Kei, Tawa, Hideki, Hirata, Yuki, Okada, Toshihiko, Kawakami, Ken, Asai, Akira, Hosomi, Shuhei, Takeuchi, Toshihisa, Fukunishi, Shinya, Inoue, Takuya, Asahi, Michio, Higuchi, Kazuhide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839862/
https://www.ncbi.nlm.nih.gov/pubmed/31703091
http://dx.doi.org/10.1371/journal.pone.0225066

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