Cargando…

CD44 and xCT: The Silver Bullet for Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension?

Detalles Bibliográficos
Autores principales:	Agrawal, Vineet, Hemnes, Anna R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Thoracic Society 2019
Materias:	Editorials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839931/ https://www.ncbi.nlm.nih.gov/pubmed/30986092 http://dx.doi.org/10.1165/rcmb.2019-0135ED

Ejemplares similares

Functional analysis of CD44 variants and xCT in canine tumours
por: Tanabe, Atsushi, et al.
Publicado: (2020)

High expression of CD44v9 and xCT in chemoresistant hepatocellular carcinoma: Potential targets by sulfasalazine
por: Wada, Fumitaka, et al.
Publicado: (2018)

Redox Regulation of Stem-like Cells Though the CD44v-xCT Axis in Colorectal Cancer: Mechanisms and Therapeutic Implications
por: Ju, Huai-Qiang, et al.
Publicado: (2016)

Sulfasalazine could modulate the CD44v9‐xCT system and enhance cisplatin‐induced cytotoxic effects in metastatic bladder cancer
por: Ogihara, Koichiro, et al.
Publicado: (2019)

xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation
por: Cai, Yi, et al.
Publicado: (2016)

Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo
por: Shin, Seung-Shick, et al.
Publicado: (2018)

Decreased xCT activity in patients associated with Helicobacter pylori infection
por: Wang, Ling, et al.
Publicado: (2022)

Genomic analysis of xCT-regulatory network in KSHV + primary effusion lymphomas
por: Qin, Zhiqiang, et al.
Publicado: (2016)

xCT inhibition sensitizes tumors to γ-radiation via glutathione reduction
por: Cobler, Lara, et al.
Publicado: (2018)

xCT Inhibition Increases Sensitivity to Vorinostat in a ROS-Dependent Manner
por: Miyamoto, Keiko, et al.
Publicado: (2020)

Sulfasalazine Sensitizes Polyhematoporphyrin-Mediated Photodynamic Therapy in Cholangiocarcinoma by Targeting xCT
por: Zheng, Yan-Wen, et al.
Publicado: (2021)

Structure‐Activity‐Relationship‐Aided Design and Synthesis of xCT Antiporter Inhibitors
por: Cirillo, Davide, et al.
Publicado: (2021)

The glutamate/cystine xCT antiporter antagonizes glutamine metabolism and reduces nutrient flexibility
por: Shin, Chun-Shik, et al.
Publicado: (2017)

Is Silver the Ultimate Antimicrobial Bullet?
por: Turner, Raymond J
Publicado: (2018)

Overexpression of xCT induces up-regulation of 14-3-3β in Kaposi's sarcoma
por: Zeng, Yan, et al.
Publicado: (2010)

Histone deacetylases inhibition by SAHA/Vorinostat normalizes the glioma microenvironment via xCT equilibration
por: Wolf, Ines M. L., et al.
Publicado: (2014)

Implication of the glutamate–cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis
por: Fournier, M., et al.
Publicado: (2017)

Cystine/Glutamate Antiporter (xCT) Is Required for Chief Cell Plasticity After Gastric Injury
por: Meyer, Anne R., et al.
Publicado: (2019)

Chemotherapeutic xCT inhibitors sorafenib and erastin unraveled with the synaptic optogenetic function analysis tool
por: Dahlmanns, Marc, et al.
Publicado: (2017)

The Role of Cystine/Glutamate Antiporter SLC7A11/xCT in the Pathophysiology of Cancer
por: Jyotsana, Nidhi, et al.
Publicado: (2022)

A xCT role in tumour-associated ferroptosis shed light on novel therapeutic options
por: Criscuolo, Daniela, et al.
Publicado: (2022)

CIC reduces xCT/SLC7A11 expression and glutamate release in glioma
por: Park, Jong-Whi, et al.
Publicado: (2023)

Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice
por: Li, Yan, et al.
Publicado: (2012)

xCT knockdown in human breast cancer cells delays onset of cancer-induced bone pain
por: Ungard, Robert G, et al.
Publicado: (2019)

Cystine–glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity
por: Arensman, Michael D., et al.
Publicado: (2019)

Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT‐targeted therapy
por: Otsuki, Yuji, et al.
Publicado: (2019)

xCT-Driven Expression of GPX4 Determines Sensitivity of Breast Cancer Cells to Ferroptosis Inducers
por: Lee, Namgyu, et al.
Publicado: (2021)

The Styryl Benzoic Acid Derivative DC10 Potentiates Radiotherapy by Targeting the xCT-Glutathione Axis
por: Sarowar, Shahin, et al.
Publicado: (2022)

Production of recombinant human xCT (SLC7A11) and reconstitution in proteoliposomes for functional studies
por: Galluccio, Michele, et al.
Publicado: (2022)

Butyrate reverses ferroptosis resistance in colorectal cancer by inducing c-Fos-dependent xCT suppression
por: He, Ying, et al.
Publicado: (2023)

Authors’ reply: role of natriuretic peptide receptor C signalling in obesity-induced heart failure with preserved ejection fraction with pulmonary hypertension
por: Agrawal, Vineet, et al.
Publicado: (2020)

The role of CD44 in epithelial–mesenchymal transition and cancer development
por: Xu, Hanxiao, et al.
Publicado: (2015)

Consensus mutagenesis approach improves the thermal stability of system x(c) (−) transporter, xCT, and enables cryo‐EM analyses
por: Oda, Kazumasa, et al.
Publicado: (2020)

Upregulation of xCT by KSHV-Encoded microRNAs Facilitates KSHV Dissemination and Persistence in an Environment of Oxidative Stress
por: Qin, Zhiqiang, et al.
Publicado: (2010)

Genomic analysis of xCT-mediated regulatory network: identification of novel targets against AIDS-associated lymphoma
por: Dai, Lu, et al.
Publicado: (2015)

xCT, not just an amino-acid transporter: a multi-functional regulator of microbial infection and associated diseases
por: Dai, Lu, et al.
Publicado: (2015)

ATF4 promotes angiogenesis and neuronal cell death and confers ferroptosis in a xCT-dependent manner
por: Chen, D, et al.
Publicado: (2017)

Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
por: Sehm, Tina, et al.
Publicado: (2016)

Development of a VLP-Based Vaccine Displaying an xCT Extracellular Domain for the Treatment of Metastatic Breast Cancer
por: Rolih, Valeria, et al.
Publicado: (2020)

ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation
por: Chen, Mei-Chun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_men02mmqlc2tq62djte0huuaq3