INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS

The fact that frailty and cognitive impairment are associated and often coexist in older adults has led to the popular view of expanding the definition of frailty to include cognitive impairment. However, there is great variability in approaches to and assumptions regarding the integrated phenotypes...

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Autores principales: Xue, Qianli, Buta, Brian, Ma, Lina, Ge, Meiling, carlson, Michelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Session 2095 (Symposium)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6840668/
http://dx.doi.org/10.1093/geroni/igz038.1464
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author Xue, Qianli
Buta, Brian
Ma, Lina
Ge, Meiling
carlson, Michelle
author_facet Xue, Qianli
Buta, Brian
Ma, Lina
Ge, Meiling
carlson, Michelle
author_sort Xue, Qianli
collection PubMed
description The fact that frailty and cognitive impairment are associated and often coexist in older adults has led to the popular view of expanding the definition of frailty to include cognitive impairment. However, there is great variability in approaches to and assumptions regarding the integrated phenotypes of physical frailty and cognitive impairment. By reviewing the theoretical underpinnings of three integrated phenotypes of physical and cognitive impairments, this talk advocates the incorporation of biological theories in phenotype development that helps determine shared and distinct pathways in the progression to physical and cognitive impairments.
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spelling pubmed-68406682019-11-15 INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS Xue, Qianli Buta, Brian Ma, Lina Ge, Meiling carlson, Michelle Innov Aging Session 2095 (Symposium) The fact that frailty and cognitive impairment are associated and often coexist in older adults has led to the popular view of expanding the definition of frailty to include cognitive impairment. However, there is great variability in approaches to and assumptions regarding the integrated phenotypes of physical frailty and cognitive impairment. By reviewing the theoretical underpinnings of three integrated phenotypes of physical and cognitive impairments, this talk advocates the incorporation of biological theories in phenotype development that helps determine shared and distinct pathways in the progression to physical and cognitive impairments. Oxford University Press 2019-11-08 /pmc/articles/PMC6840668/ http://dx.doi.org/10.1093/geroni/igz038.1464 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of The Gerontological Society of America. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Session 2095 (Symposium)
Xue, Qianli
Buta, Brian
Ma, Lina
Ge, Meiling
carlson, Michelle
INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title_full INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title_fullStr INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title_full_unstemmed INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title_short INTEGRATING FRAILTY AND COGNITIVE PHENOTYPES: THEORY, MEASUREMENT, APPLICATIONS
title_sort integrating frailty and cognitive phenotypes: theory, measurement, applications
topic Session 2095 (Symposium)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6840668/
http://dx.doi.org/10.1093/geroni/igz038.1464
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