Aberrant DNA methylation of miRNAs in Fuchs endothelial corneal dystrophy

Homeostatic maintenance of corneal endothelial cells is essential for maintenance of corneal deturgescence and transparency. In Fuchs endothelial corneal dystrophy (FECD), an accelerated loss and dysfunction of endothelial cells leads to progressively severe visual impairment. An abnormal accumulati...

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Detalles Bibliográficos
Autores principales: Pan, Peipei, Weisenberger, Daniel J., Zheng, Siyu, Wolf, Marie, Hwang, David G., Rose-Nussbaumer, Jennifer R., Jurkunas, Ula V., Chan, Matilda F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6841734/
https://www.ncbi.nlm.nih.gov/pubmed/31705138
http://dx.doi.org/10.1038/s41598-019-52727-z

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