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Circulating levels of mitochondrial uncoupling protein 2, but not prohibitin, are lower in humans with type 2 diabetes and correlate with brachial artery flow-mediated dilation

BACKGROUND: Excessive reactive oxygen species from endothelial mitochondria in type 2 diabetes individuals (T2DM) may occur through multiple related mechanisms, including production of mitochondrial reactive oxygen species (mtROS), inner mitochondrial membrane (Δψ(m)) hyperpolarization, changes in m...

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Detalles Bibliográficos
Autores principales:	Kakarla, Mamatha, Puppala, Venkata K., Tyagi, Sudhi, Anger, Amberly, Repp, Kathryn, Wang, Jingli, Ying, Rong, Widlansky, Michael E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842161/ https://www.ncbi.nlm.nih.gov/pubmed/31706320 http://dx.doi.org/10.1186/s12933-019-0956-4

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