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Engineering and characterising a novel, highly potent bispecific antibody iMab-CAP256 that targets HIV-1
The existing repertoire of HIV-1 patient derived broadly neutralising antibodies (bNAbs) that target the HIV-1 envelope glycoprotein (Env) present numerous and exciting opportunities for immune-based therapeutic and preventative strategies against HIV-1. Combination antibody therapy is required to e...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842167/ https://www.ncbi.nlm.nih.gov/pubmed/31703699 http://dx.doi.org/10.1186/s12977-019-0493-y |