Treatment with checkpoint inhibitors in a metastatic colorectal cancer patient with molecular and immunohistochemical heterogeneity in MSI/dMMR status

BACKGROUND: Analysis of deficiency in DNA mismatch repair (dMMR) is currently considered a standard molecular test in all patients with colorectal cancer (CRC) for its implications in screening, prognosis and prediction of benefit from immune checkpoint inhibitors. While the molecular heterogeneity...

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Detalles Bibliográficos
Autores principales: Loupakis, Fotios, Maddalena, Giulia, Depetris, Ilaria, Murgioni, Sabina, Bergamo, Francesca, Dei Tos, Angelo Paolo, Rugge, Massimo, Munari, Giada, Nguyen, Andrew, Szeto, Christopher, Zagonel, Vittorina, Lonardi, Sara, Fassan, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842181/
https://www.ncbi.nlm.nih.gov/pubmed/31703605
http://dx.doi.org/10.1186/s40425-019-0788-5

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