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PAK4, a target of miR-9-5p, promotes cell proliferation and inhibits apoptosis in colorectal cancer
BACKGROUND: Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. P21-activated kinase 4 (PAK4) and miR-9-5p have emerged as attractive therapeutic targets in several tumor types, but in CRC, the regulation of their biological function and their target association remain uncl...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842216/ https://www.ncbi.nlm.nih.gov/pubmed/31728150 http://dx.doi.org/10.1186/s11658-019-0182-9 |