PSMD1 and PSMD2 regulate HepG2 cell proliferation and apoptosis via modulating cellular lipid droplet metabolism

BACKGROUND: Obesity and nonalcoholic steatohepatitis (NASH) are well-known risk factors of hepatocellular carcinoma (HCC). The lipid-rich environment enhances the proliferation and metastasis abilities of tumor cells. Previous studies showed the effect of the ubiquitin–proteasome system (UPS) on tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Yanjie, Jin, Yi, Wu, Xiang, Ren, Zhuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842266/
https://www.ncbi.nlm.nih.gov/pubmed/31703613
http://dx.doi.org/10.1186/s12867-019-0141-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842266/
https://www.ncbi.nlm.nih.gov/pubmed/31703613
http://dx.doi.org/10.1186/s12867-019-0141-z

Ejemplares similares