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Paclitaxel-activated astrocytes produce mechanical allodynia in mice by releasing tumor necrosis factor-α and stromal-derived cell factor 1

BACKGROUND: Paclitaxel is a widely used and potent chemotherapeutic agent for the treatment of cancer. However, patients receiving paclitaxel often develop an acute pain syndrome for which there are few treatment options. Astrocytes play an important role in the pathogenesis of pain in multiple prec...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaojuan, Tonello, Raquel, Ling, Yuejuan, Gao, Yong-Jing, Berta, Temugin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842526/ https://www.ncbi.nlm.nih.gov/pubmed/31707979 http://dx.doi.org/10.1186/s12974-019-1619-9

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