Cargando…

Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo

AIM: To determine the clinical and allergic features of uncontrolled allergic rhinitis (UCAR) in the Democratic Republic of Congo (DRC). METHODS: Observational cross‐sectional study of 311 patients with UCAR. Allergic rhinitis was diagnosed clinically with sensitization to inhalant allergens and the...

Descripción completa

Detalles Bibliográficos
Autores principales: Kakobo, Patricia K., Kalala, Hilaire K., Tshibola, Maguy M., Kelekele, Joseph K., Nyembue, Dieudonné T., Hellings, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842815/
https://www.ncbi.nlm.nih.gov/pubmed/31532078
http://dx.doi.org/10.1002/iid3.272
_version_ 1783468094865276928
author Kakobo, Patricia K.
Kalala, Hilaire K.
Tshibola, Maguy M.
Kelekele, Joseph K.
Nyembue, Dieudonné T.
Hellings, Peter W.
author_facet Kakobo, Patricia K.
Kalala, Hilaire K.
Tshibola, Maguy M.
Kelekele, Joseph K.
Nyembue, Dieudonné T.
Hellings, Peter W.
author_sort Kakobo, Patricia K.
collection PubMed
description AIM: To determine the clinical and allergic features of uncontrolled allergic rhinitis (UCAR) in the Democratic Republic of Congo (DRC). METHODS: Observational cross‐sectional study of 311 patients with UCAR. Allergic rhinitis was diagnosed clinically with sensitization to inhalant allergens and then confirmed by skin prick test. Severity was assessed using the Visual Analog Scale (VAS), with VAS scores greater than or equal to 5 used as cut off to determine uncontrolled status. RESULTS: The mean age of UCAR patients was 30.7 ± 15.1 years and 66.9% of the patients were females. Three out of four patients had persistent UCAR while the remainder had intermittent symptoms. UCAR was associated with rhinosinusitis and asthma in 18.6% and 18% of the patients, respectively. Among UCAR patients, 95.2% were polysensitized. The allergens most frequently involved were mites (82%), cat (27.3%), and dog (26.7%). The most frequent symptoms were nasal congestion, sneezing, and runny nose. There were 44.4% of the patients treated with nasal corticosteroids and 33.1% with oral antihistamine (anti‐H1). CONCLUSIONS: This study reports on the clinical phenotype of UCAR in the DRC. The findings contribute to our understanding of UCAR in this population and may be used to implement strategies to reduce the prevalence and burden of UCAR in this setting.
format Online
Article
Text
id pubmed-6842815
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-68428152019-11-22 Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo Kakobo, Patricia K. Kalala, Hilaire K. Tshibola, Maguy M. Kelekele, Joseph K. Nyembue, Dieudonné T. Hellings, Peter W. Immun Inflamm Dis Original Research AIM: To determine the clinical and allergic features of uncontrolled allergic rhinitis (UCAR) in the Democratic Republic of Congo (DRC). METHODS: Observational cross‐sectional study of 311 patients with UCAR. Allergic rhinitis was diagnosed clinically with sensitization to inhalant allergens and then confirmed by skin prick test. Severity was assessed using the Visual Analog Scale (VAS), with VAS scores greater than or equal to 5 used as cut off to determine uncontrolled status. RESULTS: The mean age of UCAR patients was 30.7 ± 15.1 years and 66.9% of the patients were females. Three out of four patients had persistent UCAR while the remainder had intermittent symptoms. UCAR was associated with rhinosinusitis and asthma in 18.6% and 18% of the patients, respectively. Among UCAR patients, 95.2% were polysensitized. The allergens most frequently involved were mites (82%), cat (27.3%), and dog (26.7%). The most frequent symptoms were nasal congestion, sneezing, and runny nose. There were 44.4% of the patients treated with nasal corticosteroids and 33.1% with oral antihistamine (anti‐H1). CONCLUSIONS: This study reports on the clinical phenotype of UCAR in the DRC. The findings contribute to our understanding of UCAR in this population and may be used to implement strategies to reduce the prevalence and burden of UCAR in this setting. John Wiley and Sons Inc. 2019-09-18 /pmc/articles/PMC6842815/ /pubmed/31532078 http://dx.doi.org/10.1002/iid3.272 Text en © 2019 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Kakobo, Patricia K.
Kalala, Hilaire K.
Tshibola, Maguy M.
Kelekele, Joseph K.
Nyembue, Dieudonné T.
Hellings, Peter W.
Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title_full Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title_fullStr Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title_full_unstemmed Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title_short Pattern of uncontrolled allergic rhinitis in a hospital setting of Kinshasa, Democratic Republic of Congo
title_sort pattern of uncontrolled allergic rhinitis in a hospital setting of kinshasa, democratic republic of congo
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842815/
https://www.ncbi.nlm.nih.gov/pubmed/31532078
http://dx.doi.org/10.1002/iid3.272
work_keys_str_mv AT kakobopatriciak patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo
AT kalalahilairek patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo
AT tshibolamaguym patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo
AT kelekelejosephk patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo
AT nyembuedieudonnet patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo
AT hellingspeterw patternofuncontrolledallergicrhinitisinahospitalsettingofkinshasademocraticrepublicofcongo