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Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease

BACKGROUND: Drugs are very important in the etiology of nontraumatic rhabdomyolysis. CASE DESCRIPTIONS: A 16-year-old male patient with Wilson's disease was admitted for myoclonic contractions. Oral trientine was started for neurological problems and tremor on the hands due to D-penicillamine 1...

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Detalles Bibliográficos
Autores principales: Aslan, Nagehan, Yavuz, Sibel, Yildizdas, Dincer, Horoz, Ozden Ozgur, Coban, Yasemin, Tumgor, Gokhan, Bayazit, Aysun Karabay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Jaypee Brothers Medical Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842836/
https://www.ncbi.nlm.nih.gov/pubmed/31749561
http://dx.doi.org/10.5005/jp-journals-10071-23271
Descripción
Sumario:BACKGROUND: Drugs are very important in the etiology of nontraumatic rhabdomyolysis. CASE DESCRIPTIONS: A 16-year-old male patient with Wilson's disease was admitted for myoclonic contractions. Oral trientine was started for neurological problems and tremor on the hands due to D-penicillamine 1 month ago. Patient was oligoanuric, and his creatine kinase level was 15197 U/L. Rhabdomyolysis was associated with trientine, and trientine treatment was stopped. Hemodiafiltration was performed. The patient began to urinate on the 24th day. CONCLUSION: This is the first pediatric patient with rhabdomyolysis induced by trientine. Drugs used should be questioned carefully in patients with rhabdomyolysis. HOW TO CITE THIS ARTICLE: Aslan N, Yavuz S, Yildizdas D, Horoz OO, Coban Y, Tumgor G, et al. Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease. Indian J Crit Care Med 2019;23(10):489–490.