Cargando…

Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection

BACKGROUND: This study aims to investigate the descending aortic morphological alterations caused by pathological changes in acute and chronic Type B aortic dissection (TBAD) and morphological remodeling after thoracic endovascular aortic repair (TEVAR). PATIENTS AND METHODS: From February 2012 to J...

Descripción completa

Detalles Bibliográficos
Autores principales: Zha, Binshan, Qiu, Peng, Xie, Wentao, Zhang, Zhigong, Li, Yongsheng, Chen, Zhiyong, Zhu, Huagang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842900/
https://www.ncbi.nlm.nih.gov/pubmed/31806948
http://dx.doi.org/10.2147/CIA.S225305
_version_ 1783468103069335552
author Zha, Binshan
Qiu, Peng
Xie, Wentao
Zhang, Zhigong
Li, Yongsheng
Chen, Zhiyong
Zhu, Huagang
author_facet Zha, Binshan
Qiu, Peng
Xie, Wentao
Zhang, Zhigong
Li, Yongsheng
Chen, Zhiyong
Zhu, Huagang
author_sort Zha, Binshan
collection PubMed
description BACKGROUND: This study aims to investigate the descending aortic morphological alterations caused by pathological changes in acute and chronic Type B aortic dissection (TBAD) and morphological remodeling after thoracic endovascular aortic repair (TEVAR). PATIENTS AND METHODS: From February 2012 to January 2016, 86 TBAD patients undergoing TEVAR were divided into an acute group (n=63) and a chronic group (n=23). The areas of the true, false and maximal lumen and descending aorta morphological parameters, including the taper ratio (TR), oversizing ratio (OR), mismatch ratio (MR), radius of curvature (RoC) and tortuosity index (TI), were evaluated. Follow-ups were performed postoperatively before discharge, at 1 and 6 months, and yearly thereafter. RESULTS: Before TEVAR, the TR (0.57 (0.49) vs 0.74 (0.60); P < 0.05), OR (2.75 ± 1.89 vs 3.96 ± 2.27; P < 0.05) and TI (1.22 (1.19) vs 1.41 ± 0.17; P < 0.05) were significantly higher in the chronic group than in the acute group. The TEVAR technical success rate was 100%. No differences were found in 30-day and >30-day mortality between the two groups. Pathology-specific devices, such as tapered stent grafts and distal bare stents, were used more frequently in the chronic group than in the acute group (47.8% vs 23.8%, P = 0.03; 43.5% vs 12.7%, P = 0.002, respectively). The OR and TI changes that occurred after TEVAR were significantly higher in the chronic group than in the acute group (1.80 ± 0.86 vs 2.98 ± 1.85, P = 0.028; 0.00 ± 0.09 vs 0.09 ± 0.10, P < 0.001, respectively). CONCLUSION: TEVAR is a safe and effective therapy for acute and chronic TBAD. Compared to acute TBAD, chronic TBAD resulted in an adverse preoperative descending aorta morphology. Pathology-specific devices may be a feasible treatment option for endovascular repair of chronic TBAD. A larger series of cases with longer follow-up are needed to draw definitive conclusions.
format Online
Article
Text
id pubmed-6842900
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Dove
record_format MEDLINE/PubMed
spelling pubmed-68429002019-12-05 Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection Zha, Binshan Qiu, Peng Xie, Wentao Zhang, Zhigong Li, Yongsheng Chen, Zhiyong Zhu, Huagang Clin Interv Aging Original Research BACKGROUND: This study aims to investigate the descending aortic morphological alterations caused by pathological changes in acute and chronic Type B aortic dissection (TBAD) and morphological remodeling after thoracic endovascular aortic repair (TEVAR). PATIENTS AND METHODS: From February 2012 to January 2016, 86 TBAD patients undergoing TEVAR were divided into an acute group (n=63) and a chronic group (n=23). The areas of the true, false and maximal lumen and descending aorta morphological parameters, including the taper ratio (TR), oversizing ratio (OR), mismatch ratio (MR), radius of curvature (RoC) and tortuosity index (TI), were evaluated. Follow-ups were performed postoperatively before discharge, at 1 and 6 months, and yearly thereafter. RESULTS: Before TEVAR, the TR (0.57 (0.49) vs 0.74 (0.60); P < 0.05), OR (2.75 ± 1.89 vs 3.96 ± 2.27; P < 0.05) and TI (1.22 (1.19) vs 1.41 ± 0.17; P < 0.05) were significantly higher in the chronic group than in the acute group. The TEVAR technical success rate was 100%. No differences were found in 30-day and >30-day mortality between the two groups. Pathology-specific devices, such as tapered stent grafts and distal bare stents, were used more frequently in the chronic group than in the acute group (47.8% vs 23.8%, P = 0.03; 43.5% vs 12.7%, P = 0.002, respectively). The OR and TI changes that occurred after TEVAR were significantly higher in the chronic group than in the acute group (1.80 ± 0.86 vs 2.98 ± 1.85, P = 0.028; 0.00 ± 0.09 vs 0.09 ± 0.10, P < 0.001, respectively). CONCLUSION: TEVAR is a safe and effective therapy for acute and chronic TBAD. Compared to acute TBAD, chronic TBAD resulted in an adverse preoperative descending aorta morphology. Pathology-specific devices may be a feasible treatment option for endovascular repair of chronic TBAD. A larger series of cases with longer follow-up are needed to draw definitive conclusions. Dove 2019-11-06 /pmc/articles/PMC6842900/ /pubmed/31806948 http://dx.doi.org/10.2147/CIA.S225305 Text en © 2019 Zha et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Zha, Binshan
Qiu, Peng
Xie, Wentao
Zhang, Zhigong
Li, Yongsheng
Chen, Zhiyong
Zhu, Huagang
Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title_full Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title_fullStr Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title_full_unstemmed Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title_short Surgical Outcomes And Postoperative Descending Aorta Morphologic Remodeling After Thoracic Endovascular Aortic Repair For Acute And Chronic Type B Aortic Dissection
title_sort surgical outcomes and postoperative descending aorta morphologic remodeling after thoracic endovascular aortic repair for acute and chronic type b aortic dissection
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842900/
https://www.ncbi.nlm.nih.gov/pubmed/31806948
http://dx.doi.org/10.2147/CIA.S225305
work_keys_str_mv AT zhabinshan surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT qiupeng surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT xiewentao surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT zhangzhigong surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT liyongsheng surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT chenzhiyong surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection
AT zhuhuagang surgicaloutcomesandpostoperativedescendingaortamorphologicremodelingafterthoracicendovascularaorticrepairforacuteandchronictypebaorticdissection