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Actinomycin D-Activated RNase L Promotes H2A.X/H2B-Mediated DNA Damage and Apoptosis in Lung Cancer Cells

Background: Chemotherapy is an essential component for comprehensive cancer treatment, while drug resistance usually fails therapy. DNA repair mechanism of cancer cells restrains the efficacy of therapeutics targeting DNA damage. Investigating target-inducing irreversible cell death of cancer cells...

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Detalles Bibliográficos
Autores principales:	Yin, Huijing, Jiang, Zhengyu, Wang, Shuoer, Zhang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842983/ https://www.ncbi.nlm.nih.gov/pubmed/31750234 http://dx.doi.org/10.3389/fonc.2019.01086

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