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Naphthoquinone Tryptophan Hybrids: A Promising Small Molecule Scaffold for Mitigating Aggregation of Amyloidogenic Proteins and Peptides

A current challenge faced by researchers is the lack of disease-modifying therapeutics for amyloid formation that is associated with several human diseases. Although the monomeric proteins or peptides involved in various amyloidogenic diseases do not have amino acid sequence homology, there appears...

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Detalles Bibliográficos
Autores principales:	Viswanathan, Guru KrishnaKumar, Paul, Ashim, Gazit, Ehud, Segal, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843079/ https://www.ncbi.nlm.nih.gov/pubmed/31750300 http://dx.doi.org/10.3389/fcell.2019.00242

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