Cargando…

HMGB1-triggered inflammation inhibition of notoginseng leaf triterpenes against cerebral ischemia and reperfusion injury via MAPK and NF-κB signaling pathways

Ischemic stroke is a clinically common cerebrovascular disease whose main risks include necrosis, apoptosis and cerebral infarction, all caused by cerebral ischemia and reperfusion (I/R) injury. This process has particular significance for the treatment of stroke patients. Notoginseng leaf triterpen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Weijie, Zhu, Ting, Dong, Xi, Nan, Fengwei, Meng, Xiangbao, Zhou, Ping, Sun, Guibo, Sun, Xiaobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843331/ https://www.ncbi.nlm.nih.gov/pubmed/31547018 http://dx.doi.org/10.3390/biom9100512

Ejemplares similares

Notoginseng leaf triterpenes ameliorates mitochondrial oxidative injury via the NAMPT-SIRT1/2/3 signaling pathways in cerebral ischemic model rats
por: Xie, Weijie, et al.
Publicado: (2023)

Notoginseng Leaf Triterpenes Ameliorates OGD/R-Induced Neuronal Injury via SIRT1/2/3-Foxo3a-MnSOD/PGC-1α Signaling Pathways Mediated by the NAMPT-NAD Pathway
por: Xie, Weijie, et al.
Publicado: (2020)

Neuroprotective Effects of Radix Scrophulariae on Cerebral Ischemia and Reperfusion Injury via MAPK Pathways
por: Meng, Xiangbao, et al.
Publicado: (2018)

Correction: Meng, X., et al. Neuroprotective Effects of Radix Scrophulariae on Cerebral Ischemia and Reperfusion Injury via MAPK Pathways. Molecules 2018, 23, 2401
por: Meng, Xiangbao, et al.
Publicado: (2018)

Effects of notoginseng leaf triterpenes on small molecule metabolism after cerebral ischemia/reperfusion injury assessed using MALDI–MS imaging
por: Wang, Lei, et al.
Publicado: (2021)

Notoginsenoside R1 Improves Cerebral Ischemia/Reperfusion Injury by Promoting Neurogenesis via the BDNF/Akt/CREB Pathway
por: Zhu, Ting, et al.
Publicado: (2021)

Panax Notoginseng Saponins: A Review of Its Mechanisms of Antidepressant or Anxiolytic Effects and Network Analysis on Phytochemistry and Pharmacology
por: Xie, Weijie, et al.
Publicado: (2018)

Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies
por: Xie, Weijie, et al.
Publicado: (2018)

Dammarane-type Triterpene Saponins from the Flowers of Panax notoginseng
por: Wang, Jing-Rong, et al.
Publicado: (2009)

Effect of Panax notoginseng Saponins and Major Anti-Obesity Components on Weight Loss
por: Zhang, Xuelian, et al.
Publicado: (2021)

Anti-inflammatory and Cytotoxic Triterpenes from the Rot Roots of Panax notoginseng
por: Shang, Jia-Huan, et al.
Publicado: (2019)

Panax notoginseng Saponin Protects Against Diabetic Cardiomyopathy Through Lipid Metabolism Modulation
por: Zhang, Chenyang, et al.
Publicado: (2022)

Inhibiting the NLRP3 Inflammasome Activation with MCC950 Ameliorates Diabetic Encephalopathy in db/db Mice
por: Zhai, Yadong, et al.
Publicado: (2018)

Targeting Calcium Homeostasis in Myocardial Ischemia/Reperfusion Injury: An Overview of Regulatory Mechanisms and Therapeutic Reagents
por: Wang, Ruiying, et al.
Publicado: (2020)

Genes Induced by Panax Notoginseng in a Rodent Model of Ischemia-Reperfusion Injury
por: Meng, Lanqing, et al.
Publicado: (2020)

New hydroperoxylated and 20,24-epoxylated dammarane triterpenes from the rot roots of Panax notoginseng
por: Shang, Jia-Huan, et al.
Publicado: (2020)

Analysis of the transcriptome of Panax notoginseng root uncovers putative triterpene saponin-biosynthetic genes and genetic markers
por: Luo, Hongmei, et al.
Publicado: (2011)

Effect of Panax notoginseng Saponins on Focal Cerebral Ischemia-Reperfusion in Rat Models: A Meta-Analysis
por: Sun, Tao, et al.
Publicado: (2021)

Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis
por: Zhou, Ping, et al.
Publicado: (2019)

Engeletin alleviates cerebral ischemia reperfusion‐induced neuroinflammation via the HMGB1/TLR4/NF‐κB network
por: Xu, Yangyang, et al.
Publicado: (2023)

Gastrodin Ameliorates Cognitive Dysfunction in Diabetes Rat Model via the Suppression of Endoplasmic Reticulum Stress and NLRP3 Inflammasome Activation
por: Ye, Tianyuan, et al.
Publicado: (2018)

Salvianolic Acid D Alleviates Cerebral Ischemia-Reperfusion Injury by Suppressing the Cytoplasmic Translocation and Release of HMGB1-Triggered NF-κB Activation to Inhibit Inflammatory Response
por: Zhang, Wen, et al.
Publicado: (2020)

Gypenoside XVII protects against myocardial ischemia and reperfusion injury by inhibiting ER stress–induced mitochondrial injury
por: Yu, Yingli, et al.
Publicado: (2021)

Dammarane-type triterpene oligoglycosides from the leaves and stems of Panax notoginseng and their antiinflammatory activities
por: Li, Juan, et al.
Publicado: (2019)

Inhibiting HMGB1 Reduces Cerebral Ischemia Reperfusion Injury in Diabetic Mice
por: Wang, Chong, et al.
Publicado: (2016)

Hydroxysafflor Yellow A Ameliorates Myocardial Ischemia/Reperfusion Injury by Suppressing Calcium Overload and Apoptosis
por: Ye, Jingxue, et al.
Publicado: (2021)

Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling
por: Lu, Shan, et al.
Publicado: (2020)

Febuxostat Modulates MAPK/NF-κBp65/TNF-α Signaling in Cardiac Ischemia-Reperfusion Injury
por: Khan, Sana Irfan, et al.
Publicado: (2017)

Cordycepin Protects against Hepatic Ischemia/Reperfusion Injury via Inhibiting MAPK/NF-κB Pathway
por: Ding, Jiameng, et al.
Publicado: (2022)

Saponins in Chinese Herbal Medicine Exerts Protection in Myocardial Ischemia–Reperfusion Injury: Possible Mechanism and Target Analysis
por: Wang, Ruiying, et al.
Publicado: (2021)

Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy
por: Zhou, Ping, et al.
Publicado: (2019)

Correction: Zhou, P., et al. Notoginsenoside R1 Ameliorates Diabetic Retinopathy through PINK1-Dependent Activation of Mitophagy. Cells, 2019, 8, 213
por: Zhou, Ping, et al.
Publicado: (2020)

Huang Qi Tong Bi Decoction Attenuates Myocardial Ischemia-Reperfusion Injury via HMGB1/TLR/NF-κB Pathway
por: Liu, Kun, et al.
Publicado: (2019)

microRNA-130a-5p suppresses myocardial ischemia reperfusion injury by downregulating the HMGB2/NF-κB axis
por: Li, Yong, et al.
Publicado: (2021)

Iminostilbene, a novel small-molecule modulator of PKM2, suppresses macrophage inflammation in myocardial ischemia–reperfusion injury
por: Lu, Shan, et al.
Publicado: (2020)

Correction to: Bilobalide protects against ischemia/reperfusion-induced oxidative stress and inflammatory responses via the MAPK/NF-κB pathways in rats
por: Li, Ying, et al.
Publicado: (2020)

Down-regulation of nuclear HMGB1 reduces ischemia-induced HMGB1 translocation and release and protects against liver ischemia-reperfusion injury
por: Zhao, Guangyuan, et al.
Publicado: (2017)

Aucubin Attenuates Liver Ischemia-Reperfusion Injury by Inhibiting the HMGB1/TLR-4/NF-κB Signaling Pathway, Oxidative Stress, and Apoptosis
por: Zhang, Shilong, et al.
Publicado: (2020)

Kaempferol Improves Lung Ischemia-Reperfusion Injury via Antiinflammation and Antioxidative Stress Regulated by SIRT1/HMGB1/NF-κB Axis
por: Yang, Chunli, et al.
Publicado: (2020)

Dl-3-n-Butylphthalide (NBP) Mitigates Muscular Injury Induced by Limb Ischemia/Reperfusion in Mice through the HMGB1/TLR4/NF-κB Pathway
por: Sun, Huanhuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gjbpipv203t4jrq5c1qao7es9v