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A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela

With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introd...

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Autores principales: McMahon, Elizabeth, Encinales, Liliana, Navarro Encinales, Carlos, Vielma, Silvana, Pacheco, Nelly, Avendaño Echavez, Lil Geraldine, Acosta Rodríguez, Sandra, Calderon, Milena, Encinales Sanabria, Silvia, Encinales Sanabria, Lorena, Serrano Bernal, Ericka, Gonzaléz Coba, Andrés, Jiménez, Dennys, Simon, Gary, Chang, Aileen Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843364/
https://www.ncbi.nlm.nih.gov/pubmed/31623165
http://dx.doi.org/10.3390/microorganisms7100458
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author McMahon, Elizabeth
Encinales, Liliana
Navarro Encinales, Carlos
Vielma, Silvana
Pacheco, Nelly
Avendaño Echavez, Lil Geraldine
Acosta Rodríguez, Sandra
Calderon, Milena
Encinales Sanabria, Silvia
Encinales Sanabria, Lorena
Serrano Bernal, Ericka
Gonzaléz Coba, Andrés
Jiménez, Dennys
Simon, Gary
Chang, Aileen Y.
author_facet McMahon, Elizabeth
Encinales, Liliana
Navarro Encinales, Carlos
Vielma, Silvana
Pacheco, Nelly
Avendaño Echavez, Lil Geraldine
Acosta Rodríguez, Sandra
Calderon, Milena
Encinales Sanabria, Silvia
Encinales Sanabria, Lorena
Serrano Bernal, Ericka
Gonzaléz Coba, Andrés
Jiménez, Dennys
Simon, Gary
Chang, Aileen Y.
author_sort McMahon, Elizabeth
collection PubMed
description With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introduction to evaluate disease burden and the strength of current vaccination programs. This study seeks to aid in that decision-making process by examining the acceptability and feasibility of dengue vaccine introduction in Barranquilla, Colombia, and Merida, Venezuela. Surveys were administered February–June of 2018 for three groups: patients (n = 351), health professionals (n = 197), and government officials (n = 26). In Barranquilla, most respondents reported dengue to be a moderate-severe problem, that a dengue vaccine would be useful in their communities, and that their current vaccination programs could handle the addition of a new vaccine. In Venezuela, respondents were less likely to view dengue as a major concern and listed multiple barriers to not just dengue vaccine introduction, but to providing current vaccines as well. Further work is needed in Colombia to more objectively assess the country’s readiness as a whole for a future dengue vaccine. As political and social unrest continues in Venezuela, however, future initiatives should focus on trust and capacity building. This study can serve as a framework for future assessments of the acceptability and feasibility of a dengue vaccine in both targeted areas and on larger scales.
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spelling pubmed-68433642019-11-25 A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela McMahon, Elizabeth Encinales, Liliana Navarro Encinales, Carlos Vielma, Silvana Pacheco, Nelly Avendaño Echavez, Lil Geraldine Acosta Rodríguez, Sandra Calderon, Milena Encinales Sanabria, Silvia Encinales Sanabria, Lorena Serrano Bernal, Ericka Gonzaléz Coba, Andrés Jiménez, Dennys Simon, Gary Chang, Aileen Y. Microorganisms Article With one vaccine on the market and others in clinical trials, policy makers in dengue endemic regions face the decision of whether to introduce a dengue vaccine in their communities. The World Health Organization (WHO) recommends that individualized assessments be conducted before any vaccine introduction to evaluate disease burden and the strength of current vaccination programs. This study seeks to aid in that decision-making process by examining the acceptability and feasibility of dengue vaccine introduction in Barranquilla, Colombia, and Merida, Venezuela. Surveys were administered February–June of 2018 for three groups: patients (n = 351), health professionals (n = 197), and government officials (n = 26). In Barranquilla, most respondents reported dengue to be a moderate-severe problem, that a dengue vaccine would be useful in their communities, and that their current vaccination programs could handle the addition of a new vaccine. In Venezuela, respondents were less likely to view dengue as a major concern and listed multiple barriers to not just dengue vaccine introduction, but to providing current vaccines as well. Further work is needed in Colombia to more objectively assess the country’s readiness as a whole for a future dengue vaccine. As political and social unrest continues in Venezuela, however, future initiatives should focus on trust and capacity building. This study can serve as a framework for future assessments of the acceptability and feasibility of a dengue vaccine in both targeted areas and on larger scales. MDPI 2019-10-16 /pmc/articles/PMC6843364/ /pubmed/31623165 http://dx.doi.org/10.3390/microorganisms7100458 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
McMahon, Elizabeth
Encinales, Liliana
Navarro Encinales, Carlos
Vielma, Silvana
Pacheco, Nelly
Avendaño Echavez, Lil Geraldine
Acosta Rodríguez, Sandra
Calderon, Milena
Encinales Sanabria, Silvia
Encinales Sanabria, Lorena
Serrano Bernal, Ericka
Gonzaléz Coba, Andrés
Jiménez, Dennys
Simon, Gary
Chang, Aileen Y.
A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title_full A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title_fullStr A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title_full_unstemmed A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title_short A Dengue Vaccine: Will It be Accepted and Is It Feasible? Lessons from Barranquilla, Colombia, and Merida, Venezuela
title_sort dengue vaccine: will it be accepted and is it feasible? lessons from barranquilla, colombia, and merida, venezuela
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843364/
https://www.ncbi.nlm.nih.gov/pubmed/31623165
http://dx.doi.org/10.3390/microorganisms7100458
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