Cargando…

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres

Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma. Gossypol, a natural polyphenolic compound, has been studied as a monotherapy or...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hee Yeon, Lee, Byung Il, Jeon, Ji Hoon, Kim, Dong Keon, Kang, Seok-Gu, Shim, Jin-Kyoung, Kim, Soo Youl, Kang, Sang Won, Jang, Hyonchol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843396/ https://www.ncbi.nlm.nih.gov/pubmed/31658771 http://dx.doi.org/10.3390/biom9100595

Ejemplares similares

Farnesyl diphosphate synthase is important for the maintenance of glioblastoma stemness
por: Kim, Hee Yeon, et al.
Publicado: (2018)

Combinatorial Therapeutic Effect of Inhibitors of Aldehyde Dehydrogenase and Mitochondrial Complex I, and the Chemotherapeutic Drug, Temozolomide against Glioblastoma Tumorspheres
por: Park, Hun Ho, et al.
Publicado: (2021)

Combined effects of niclosamide and temozolomide against human glioblastoma tumorspheres
por: Oh, Hyeong-Cheol, et al.
Publicado: (2020)

Concurrent Chemoradiotherapy with Temozolomide Followed by Adjuvant Temozolomide for Newly Diagnosed Glioblastoma Patients: A Retrospective Multicenter Observation Study in Korea
por: Kim, Byung Sup, et al.
Publicado: (2017)

Repurposing Penfluridol in Combination with Temozolomide for the Treatment of Glioblastoma
por: Kim, Hyungsin, et al.
Publicado: (2019)

Association between survival and levetiracetam use in glioblastoma patients treated with temozolomide chemoradiotherapy
por: Roh, Tae Hoon, et al.
Publicado: (2020)

Inhibiting stemness and invasive properties of glioblastoma tumorsphere by combined treatment with temozolomide and a newly designed biguanide (HL156A)
por: Choi, Junjeong, et al.
Publicado: (2016)

The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer
por: Lee, Seon-Hyeong, et al.
Publicado: (2020)

Phospholipase D1 inhibition sensitizes glioblastoma to temozolomide and suppresses its tumorigenicity
por: Kang, Dong Woo, et al.
Publicado: (2020)

Cholesterol Synthesis Is Important for Breast Cancer Cell Tumor Sphere Formation and Invasion
por: Kim, Hee Yeon, et al.
Publicado: (2022)

Long-term outcomes of concomitant chemoradiotherapy with temozolomide for newly diagnosed glioblastoma patients: A single-center analysis
por: Roh, Tae Hoon, et al.
Publicado: (2017)

Prediction of Response to Concurrent Chemoradiotherapy with Temozolomide in Glioblastoma: Application of Immediate Post-Operative Dynamic Susceptibility Contrast and Diffusion-Weighted MR Imaging
por: Lee, Eun Kyoung, et al.
Publicado: (2015)

Phosphorylation of OCT4 Serine 236 Inhibits Germ Cell Tumor Growth by Inducing Differentiation
por: Kim, Dong Keon, et al.
Publicado: (2020)

Tumor Microenvironment and Genes Affecting the Prognosis of Temozolomide-Treated Glioblastoma
por: Jang, Yena, et al.
Publicado: (2023)

OKN-007 Increases temozolomide (TMZ) Sensitivity and Suppresses TMZ-Resistant Glioblastoma (GBM) Tumor Growth()()
por: Towner, Rheal A., et al.
Publicado: (2018)

Suppressing TRAP1 sensitizes glioblastoma multiforme cells to temozolomide
por: Wang, Nan, et al.
Publicado: (2021)

Etomoxir, a carnitine palmitoyltransferase 1 inhibitor, combined with temozolomide reduces stemness and invasiveness in patient-derived glioblastoma tumorspheres
por: Shim, Jin-Kyoung, et al.
Publicado: (2022)

Cytotoxicity of enantiomers of gossypol.
por: Joseph, A. E., et al.
Publicado: (1986)

Migration and invasion of drug-resistant lung adenocarcinoma cells are dependent on mitochondrial activity
por: Jeon, Ji Hoon, et al.
Publicado: (2016)

Reply to Krupenko et al., Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382”
por: Lee, Seon-Hyeong, et al.
Publicado: (2021)

Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models
por: Jarzabek, M A, et al.
Publicado: (2014)

SEZ6L2 Is an Important Regulator of Drug-Resistant Cells and Tumor Spheroid Cells in Lung Adenocarcinoma
por: Lee, Jang-Seok, et al.
Publicado: (2020)

Continuous Low-Dose Temozolomide Chemotherapy and Microvessel Density in Recurrent Glioblastoma
por: Woo, Jong-Yun, et al.
Publicado: (2015)

Temozolomide resistance in glioblastoma multiforme
por: Lee, Sang Y.
Publicado: (2016)

Temozolomide during and after Radiotherapy for Newly Diagnosed Glioblastomas : A Prospective Multicenter Study of Korean Patients
por: Joo, Jin-Deok, et al.
Publicado: (2012)

Characterization of gossypol biosynthetic pathway
por: Tian, Xiu, et al.
Publicado: (2018)

Metformin treatment reduces temozolomide resistance of glioblastoma cells
por: Yang, Seung Ho, et al.
Publicado: (2016)

Transcriptome profiling-based identification of prognostic subtypes and multi-omics signatures of glioblastoma
por: Park, Junseong, et al.
Publicado: (2019)

Gossypol Treatment Restores Insufficient Apoptotic Function of DFF40/CAD in Human Glioblastoma Cells
por: Martínez-Escardó, Laura, et al.
Publicado: (2021)

Oxoglutarate Carrier Inhibition Reduced Melanoma Growth and Invasion by Reducing ATP Production
por: Lee, Jae-Seon, et al.
Publicado: (2020)

Autophagy enhancement contributes to the synergistic effect of vitamin D in temozolomide-based glioblastoma chemotherapy
por: BAK, DONG-HO, et al.
Publicado: (2016)

One-Year Outcome of Multiple Blood–Brain Barrier Disruptions With Temozolomide for the Treatment of Glioblastoma
por: Park, So Hee, et al.
Publicado: (2020)

Auranofin Inhibits RANKL-Induced Osteoclastogenesis by Suppressing Inhibitors of κB Kinase and Inflammasome-Mediated Interleukin-1β Secretion
por: Kim, Hyun Young, et al.
Publicado: (2019)

Glucose Deprivation Induces Cancer Cell Death through Failure of ROS Regulation
por: Kang, Mingyu, et al.
Publicado: (2023)

Gossypol detoxification in the rumen and Helicoverpa armigera larvae: A review
por: Wang, Wei-Kang, et al.
Publicado: (2021)

Effect of Peptide Receptor Radionuclide Therapy in Combination with Temozolomide against Tumor Angiogenesis in a Glioblastoma Model
por: Lee, Sang Hee, et al.
Publicado: (2021)

Accelerated hyperfractionation plus temozolomide in glioblastoma
por: Kaul, David, et al.
Publicado: (2016)

Strategies of temozolomide in future glioblastoma treatment
por: Lee, Chooi Yeng
Publicado: (2017)

Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma
por: Saha, Dipongkor, et al.
Publicado: (2020)

Gossypol Toxicity from Cottonseed Products
por: Gadelha, Ivana Cristina N., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rn5p7vhchlhbapjskm3rqe5jjk