Mesoporous Silica Nanoparticles Trigger Liver and Kidney Injury and Fibrosis Via Altering TLR4/NF-κB, JAK2/STAT3 and Nrf2/HO-1 Signaling in Rats

Mesoporous silica nanoparticles (MSNs) represent a promising inorganic platform for multiple biomedical applications. Previous studies have reported MSNs-induced hepatic and renal toxicity; however, the toxic mechanism remains unclear. This study aimed to investigate MSNs-induced hepatic and nephrot...

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Detalles Bibliográficos
Autores principales: Mahmoud, Ayman M., Desouky, Ekram M., Hozayen, Walaa G., Bin-Jumah, May, El-Nahass, El-Shaymaa, Soliman, Hanan A., Farghali, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843412/
https://www.ncbi.nlm.nih.gov/pubmed/31557909
http://dx.doi.org/10.3390/biom9100528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843412/
https://www.ncbi.nlm.nih.gov/pubmed/31557909
http://dx.doi.org/10.3390/biom9100528

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