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Enhanced Solubility and Anticancer Potential of Mansonone G By β-Cyclodextrin-Based Host-Guest Complexation: A Computational and Experimental Study

Mansonone G (MG), a plant-derived compound isolated from the heartwood of Mansonia gagei, possesses a potent antitumor effect on several kinds of malignancy. However, its poor solubility limits the use for practical applications. Beta-cyclodextrin (βCD), a cyclic oligosaccharide composed of seven (1...

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Detalles Bibliográficos
Autores principales: Mahalapbutr, Panupong, Wonganan, Piyanuch, Charoenwongpaiboon, Thanapon, Prousoontorn, Manchumas, Chavasiri, Warinthorn, Rungrotmongkol, Thanyada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843486/
https://www.ncbi.nlm.nih.gov/pubmed/31569832
http://dx.doi.org/10.3390/biom9100545