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Enhanced Solubility and Anticancer Potential of Mansonone G By β-Cyclodextrin-Based Host-Guest Complexation: A Computational and Experimental Study
Mansonone G (MG), a plant-derived compound isolated from the heartwood of Mansonia gagei, possesses a potent antitumor effect on several kinds of malignancy. However, its poor solubility limits the use for practical applications. Beta-cyclodextrin (βCD), a cyclic oligosaccharide composed of seven (1...
Autores principales: | Mahalapbutr, Panupong, Wonganan, Piyanuch, Charoenwongpaiboon, Thanapon, Prousoontorn, Manchumas, Chavasiri, Warinthorn, Rungrotmongkol, Thanyada |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843486/ https://www.ncbi.nlm.nih.gov/pubmed/31569832 http://dx.doi.org/10.3390/biom9100545 |
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