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In Vitro Evaluation of Neutral Aryloximes as Reactivators for Electrophorus eel Acetylcholinesterase Inhibited by Paraoxon

Casualties caused by organophosphorus pesticides are a burden for health systems in developing and poor countries. Such compounds are potent acetylcholinesterase irreversible inhibitors, and share the toxic profile with nerve agents. Pyridinium oximes are the only clinically available antidotes agai...

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Detalles Bibliográficos
Autores principales: Kitagawa, Daniel A. S., Cavalcante, Samir F. de A., de Paula, Reuel L., Rodrigues, Rafael B., Bernardo, Leandro B., da Silva, Munique C. J., da Silva, Thiago N., dos Santos, Wellington V., Granjeiro, José M., de Almeida, Joyce S. F. D., Barcellos, Marcos C., de A. Correa, Ana Beatriz, França, Tanos C. C., Kuča, Kamil, Simas, Alessandro B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843506/
https://www.ncbi.nlm.nih.gov/pubmed/31597234
http://dx.doi.org/10.3390/biom9100583