Cargando…

Sustained relief of trigeminal neuropathic pain by a blood–brain barrier penetrable PPAR gamma agonist

The blood–brain barrier (BBB) and blood–nerve barrier ensure protection of the nervous system but pose a challenge for the treatment of pain since it restricts passage of many therapeutic drugs. Although it is unknown which blood–neural barrier is more relevant, or whether permeabilities are the sam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Morgan, Hu, Min, Montera, Marena A, Westlund, Karin N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843736/ https://www.ncbi.nlm.nih.gov/pubmed/31588847 http://dx.doi.org/10.1177/1744806919884498

Ejemplares similares

Trigeminal neuropathic pain is alleviated by inhibition of Ca(v)3.3 T-type calcium channels in mice
por: Montera, Marena, et al.
Publicado: (2020)

Building and Testing PPARγ Therapeutic ELB00824 with an Improved Therapeutic Window for Neuropathic Pain
por: Westlund, Karin N., et al.
Publicado: (2020)

The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model
por: Vigil, Jacob M., et al.
Publicado: (2020)

Rapid Generation and Molecular Docking Analysis of Single-Chain Fragment Variable (scFv) Antibody Selected by Ribosome Display Targeting Cholecystokinin B Receptor (CCK-BR) for Reduction of Chronic Neuropathic Pain
por: Kunamneni, Adinarayana, et al.
Publicado: (2023)

Manganese-enhanced MRI reveals changes within brain anxiety and aversion circuitry in rats with chronic neuropathic pain- and anxiety-like behaviors
por: McIlwrath, Sabrina L., et al.
Publicado: (2020)

Orofacial neuropathic pain mouse model induced by Trigeminal Inflammatory Compression (TIC) of the infraorbital nerve
por: Ma, Fei, et al.
Publicado: (2012)

Pain-related behavioral and electrophysiological actions of dynorphin A (1-17)
por: LaVigne, Justin E, et al.
Publicado: (2023)

Pathophysiology of Post-Traumatic Trigeminal Neuropathic Pain
por: Korczeniewska, Olga A., et al.
Publicado: (2022)

Histamine, histamine receptors, and neuropathic pain relief
por: Obara, Ilona, et al.
Publicado: (2019)

TLR8 in the Trigeminal Ganglion Contributes to the Maintenance of Trigeminal Neuropathic Pain in Mice
por: Zhao, Lin-Xia, et al.
Publicado: (2020)

Pharmacological Treatment of Chemotherapy-Induced Neuropathic Pain: PPARγ Agonists as a Promising Tool
por: Quintão, Nara Lins Meira, et al.
Publicado: (2019)

Regional brain morphology predicts pain relief in trigeminal neuralgia
por: Hung, Peter Shih-Ping, et al.
Publicado: (2021)

Predicting pain relief: Use of pre-surgical trigeminal nerve diffusion metrics in trigeminal neuralgia
por: Hung, Peter S.-P., et al.
Publicado: (2017)

Pathological Mechanisms and Therapeutic Targets for Trigeminal Neuropathic Pain
por: Bista, Pawan, et al.
Publicado: (2019)

Food-Derived Natural Compounds for Pain Relief in Neuropathic Pain
por: Lim, Eun Yeong, et al.
Publicado: (2016)

CXCL10 and CXCR3 in the Trigeminal Ganglion Contribute to Trigeminal Neuropathic Pain in Mice
por: Ju, Yuan-Yuan, et al.
Publicado: (2021)

Trigeminal neuropathic pain causes changes in affective processing of pain in rats
por: Araya, Erika I, et al.
Publicado: (2022)

Radiosurgery for Epidermoid Tumors: Dramatic Pain Relief from Trigeminal Neuralgia
por: Kida, Yoshihisa, et al.
Publicado: (2019)

Maresin-2 inhibits inflammatory and neuropathic trigeminal pain and reduces neuronal activation in the trigeminal ganglion
por: Lopes, Raphael Vieira, et al.
Publicado: (2023)

The effect of IL-6/Piezo2 on the trigeminal neuropathic pain
por: Liu, MingXing, et al.
Publicado: (2021)

Single-Dose P2 X4R Single-Chain Fragment Variable Antibody Permanently Reverses Chronic Pain in Male Mice
por: Westlund, Karin N., et al.
Publicado: (2021)

Tetrodotoxin, a Potential Drug for Neuropathic and Cancer Pain Relief?
por: González-Cano, Rafael, et al.
Publicado: (2021)

Emodin alleviates chronic constriction injury-induced neuropathic pain and inflammation via modulating PPAR-gamma pathway
por: Badshah, Ismail, et al.
Publicado: (2023)

Sustained relief of neuropathic pain by AAV-targeted expression of CBD3 peptide in rat dorsal root ganglion
por: Fischer, G, et al.
Publicado: (2014)

Immediate Pain Relief Elicited After Radiosurgery for Classical and Symptomatic Trigeminal Neuralgia
por: Gorgulho, Alessandra, et al.
Publicado: (2019)

Relief from neuropathic pain by blocking of the platelet-activating factor–pain loop
por: Shindou, Hideo, et al.
Publicado: (2017)

Colocalized Structural and Functional Changes in the Cortex of Patients with Trigeminal Neuropathic Pain
por: DaSilva, Alexandre F., et al.
Publicado: (2008)

Update on neuropathic pain treatment for trigeminal neuralgia: The pharmacological and surgical options
por: Al-Quliti, Khalid W.
Publicado: (2015)

Persistent, neuropathic-like trigeminal pain after dental implant loading
por: Amadou-Diaw, Ndiaye, et al.
Publicado: (2022)

Can treatment success with 5% lidocaine medicated plaster be predicted in cancer pain with neuropathic components or trigeminal neuropathic pain?
por: Kern, Kai-Uwe, et al.
Publicado: (2013)

The brain-penetrant 5-HT(7) receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain
por: Santello, Mirko, et al.
Publicado: (2017)

Pain Relief in a Trigeminal Neuralgia Model via Optogenetic Inhibition on Trigeminal Ganglion Itself With Flexible Optic Fiber Cannula
por: KC, Elina, et al.
Publicado: (2022)

PPARα Agonist WY-14643 Relieves Neuropathic Pain through SIRT1-Mediated Deacetylation of NF-κB
por: Wen, Wanshun, et al.
Publicado: (2020)

Microvascular decompression in trigeminal neuralgia: predictors of pain relief, complication avoidance, and lessons learned
por: Herta, Johannes, et al.
Publicado: (2021)

Potassium channels as a potential therapeutic target for trigeminal neuropathic and inflammatory pain
por: Takeda, Mamoru, et al.
Publicado: (2011)

Aberrant TRPV1 Expression in Heat Hyperalgesia Associated with Trigeminal Neuropathic Pain
por: Urano, Hiroko, et al.
Publicado: (2012)

Peripheral Neuropathic Facial/Trigeminal Pain and RANTES/CCL5 in Jawbone Cavitation
por: Lechner, Johann, et al.
Publicado: (2015)

Amplified parabrachial nucleus activity in a rat model of trigeminal neuropathic pain
por: Uddin, Olivia, et al.
Publicado: (2018)

Sex Difference in Trigeminal Neuropathic Pain Response to Exercise: Role of Oxidative Stress
por: Rostami, Zahra, et al.
Publicado: (2020)

Early Blockade of EphA4 Pathway Reduces Trigeminal Neuropathic Pain
por: Kim, Min-Ji, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_f8d93seu6lebtgenucc428vhud