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Blockade of Intranigral and Systemic D3 Receptors Stimulates Motor Activity in the Rat Promoting a Reciprocal Interaction among Glutamate, Dopamine, and GABA

In vivo activation of dopamine D3 receptors (D3Rs) depresses motor activity. D3Rs are widely expressed in subthalamic, striatal, and dendritic dopaminergic inputs into the substantia nigra pars reticulata (SNr). In vitro studies showed that nigral D3Rs modulate their neurotransmitter release; thus,...

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Detalles Bibliográficos
Autores principales: Rodríguez-Sánchez, Marina, Escartín-Pérez, Rodrigo Erick, Leyva-Gómez, Gerardo, Avalos-Fuentes, José Arturo, Paz-Bermúdez, Francisco Javier, Loya-López, Santiago Iván, Aceves, Jorge, Erlij, David, Cortés, Hernán, Florán, Benjamín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843834/
https://www.ncbi.nlm.nih.gov/pubmed/31547016
http://dx.doi.org/10.3390/biom9100511