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An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges

BACKGROUND: Pharmacy interventions are a subset of public health interventions and its research is usually performed within the scope of a trial. The economic evaluation of pharmacy interventions requires certain considerations which have some similarities to those of public health interventions and...

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Autores principales: Costa, Suzete, Cary, Maria, Helling, Dennis K., Pereira, João, Mateus, Céu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844055/
https://www.ncbi.nlm.nih.gov/pubmed/31711541
http://dx.doi.org/10.1186/s13643-019-1177-3
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author Costa, Suzete
Cary, Maria
Helling, Dennis K.
Pereira, João
Mateus, Céu
author_facet Costa, Suzete
Cary, Maria
Helling, Dennis K.
Pereira, João
Mateus, Céu
author_sort Costa, Suzete
collection PubMed
description BACKGROUND: Pharmacy interventions are a subset of public health interventions and its research is usually performed within the scope of a trial. The economic evaluation of pharmacy interventions requires certain considerations which have some similarities to those of public health interventions and to economic evaluations alongside trials. The objective of this research is to perform an overview of systematic reviews of economic evaluations of pharmacy services and triangulate results with recommendations for economic evaluations of both public health interventions and alongside trials. METHODS: (1) Exploratory review of recommendations on the economic evaluation of public health interventions, (2) exploratory review of recommendations for conducting economic evaluations alongside trials, (3) overview of systematic reviews of economic evaluations of pharmacy interventions (protocol registered with PROSPERO 2016 outlining information sources, inclusion criteria, appraisal of reviews and synthesis methods). RESULTS: Fourteen systematic reviews containing 75 index publications were included. Reviews reported favorable economic findings for 71% of studies with full economic evaluations. The types of economic analysis are diverse. Two critical quality domains are absent from most reviews. Key findings include the following: certain types of risk of bias, wider scope of study designs, and most economic quality criteria met but some issues unresolved or unclear. Triangulation revealed additional gaps. Limitations include choice of critical quality domains and potential biases in the overview process. CONCLUSIONS: Economic evaluations of pharmacy-based public health interventions seem to follow most economic quality criteria, but there are still some issues in certain key areas to improve. These findings may assist in improving the design of pilot trials of economic evaluations in pharmacy, leading to robust evidence for payers. Based on the findings, we propose a methodological approach for the economic evaluation of pharmacy-based public health interventions. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016032768
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spelling pubmed-68440552019-11-15 An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges Costa, Suzete Cary, Maria Helling, Dennis K. Pereira, João Mateus, Céu Syst Rev Research BACKGROUND: Pharmacy interventions are a subset of public health interventions and its research is usually performed within the scope of a trial. The economic evaluation of pharmacy interventions requires certain considerations which have some similarities to those of public health interventions and to economic evaluations alongside trials. The objective of this research is to perform an overview of systematic reviews of economic evaluations of pharmacy services and triangulate results with recommendations for economic evaluations of both public health interventions and alongside trials. METHODS: (1) Exploratory review of recommendations on the economic evaluation of public health interventions, (2) exploratory review of recommendations for conducting economic evaluations alongside trials, (3) overview of systematic reviews of economic evaluations of pharmacy interventions (protocol registered with PROSPERO 2016 outlining information sources, inclusion criteria, appraisal of reviews and synthesis methods). RESULTS: Fourteen systematic reviews containing 75 index publications were included. Reviews reported favorable economic findings for 71% of studies with full economic evaluations. The types of economic analysis are diverse. Two critical quality domains are absent from most reviews. Key findings include the following: certain types of risk of bias, wider scope of study designs, and most economic quality criteria met but some issues unresolved or unclear. Triangulation revealed additional gaps. Limitations include choice of critical quality domains and potential biases in the overview process. CONCLUSIONS: Economic evaluations of pharmacy-based public health interventions seem to follow most economic quality criteria, but there are still some issues in certain key areas to improve. These findings may assist in improving the design of pilot trials of economic evaluations in pharmacy, leading to robust evidence for payers. Based on the findings, we propose a methodological approach for the economic evaluation of pharmacy-based public health interventions. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42016032768 BioMed Central 2019-11-11 /pmc/articles/PMC6844055/ /pubmed/31711541 http://dx.doi.org/10.1186/s13643-019-1177-3 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Costa, Suzete
Cary, Maria
Helling, Dennis K.
Pereira, João
Mateus, Céu
An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title_full An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title_fullStr An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title_full_unstemmed An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title_short An overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
title_sort overview of systematic reviews of economic evaluations of pharmacy-based public health interventions: addressing methodological challenges
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844055/
https://www.ncbi.nlm.nih.gov/pubmed/31711541
http://dx.doi.org/10.1186/s13643-019-1177-3
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