CDK12 Activity-Dependent Phosphorylation Events in Human Cells

We asked whether the C-terminal repeat domain (CTD) kinase, CDK12/CyclinK, phosphorylates substrates in addition to the CTD of RPB1, using our CDK12(analog-sensitive) HeLa cell line to investigate CDK12 activity-dependent phosphorylation events in human cells. Characterizing the phospho-proteome bef...

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Detalles Bibliográficos
Autores principales: Bartkowiak, Bartlomiej, Yan, Christopher M., Soderblom, Erik J., Greenleaf, Arno L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844070/
https://www.ncbi.nlm.nih.gov/pubmed/31652541
http://dx.doi.org/10.3390/biom9100634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844070/
https://www.ncbi.nlm.nih.gov/pubmed/31652541
http://dx.doi.org/10.3390/biom9100634

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