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Cytotoxicity Of Chalcone Of Eugenia aquea Burm F. Leaves Against T47D Breast Cancer Cell Lines And Its Prediction As An Estrogen Receptor Antagonist Based On Pharmacophore-Molecular Dynamics Simulation

BACKGROUND: The 2ʹ,4ʹ-dihydroxy-6-methoxy-3,5-3-dimethylchalcone (ChalcEA) isolated from Eugenia aquea Burm f. leaves has potential anticancer activity against human breast-adenocarcinoma cell lines (MCF-7) with an IC(50) value of 250 µM. However, its apoptotic activity on the T47D breast cancer cel...

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Detalles Bibliográficos
Autores principales:	Muchtaridi, Muchtaridi, Yusuf, Muhammad, Syahidah, Hasna Nur, Subarnas, Anas, Zamri, Adel, Bryant, Sharon D, Langer, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844098/ https://www.ncbi.nlm.nih.gov/pubmed/31807030 http://dx.doi.org/10.2147/AABC.S217205

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