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IFNβ-producing CX3CR1(+) macrophages promote T-regulatory cell expansion and tumor growth in the APC(min/+) / Bacteroides fragilis colon cancer model
Increased T-regulatory cell activity drives tumor progression in the compound APC(min/+)/enterotoxic Bacteroides fragilis colon cancer model. At the same time, how microbially-induced inflammation promotes T-regulatory cell expansion in the dysplastic intestine remains poorly described. Analysis of...
Autores principales: | Gu, Tao, Li, Qingsheng, Egilmez, Nejat K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844303/ https://www.ncbi.nlm.nih.gov/pubmed/31741765 http://dx.doi.org/10.1080/2162402X.2019.1665975 |
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