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IFNβ-producing CX3CR1(+) macrophages promote T-regulatory cell expansion and tumor growth in the APC(min/+) / Bacteroides fragilis colon cancer model

Increased T-regulatory cell activity drives tumor progression in the compound APC(min/+)/enterotoxic Bacteroides fragilis colon cancer model. At the same time, how microbially-induced inflammation promotes T-regulatory cell expansion in the dysplastic intestine remains poorly described. Analysis of...

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Detalles Bibliográficos
Autores principales: Gu, Tao, Li, Qingsheng, Egilmez, Nejat K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844303/
https://www.ncbi.nlm.nih.gov/pubmed/31741765
http://dx.doi.org/10.1080/2162402X.2019.1665975

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