HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma

HVEM (Herpes Virus Entry Mediator) engagement of BTLA (B and T Lymphocyte Attenuator) triggers inhibitory signals in T cells and could play a role in evading antitumor immunity. Here, HVEM expression levels in melanoma metastases were analyzed by immunohistochemistry, correlated with overall surviva...

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Detalles Bibliográficos
Autores principales: Malissen, Nausicaa, Macagno, Nicolas, Granjeaud, Samuel, Granier, Clémence, Moutardier, Vincent, Gaudy-Marqueste, Caroline, Habel, Nadia, Mandavit, Marion, Guillot, Bernard, Pasero, Christine, Tartour, Eric, Ballotti, Robert, Grob, Jean-Jacques, Olive, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844309/
https://www.ncbi.nlm.nih.gov/pubmed/31741766
http://dx.doi.org/10.1080/2162402X.2019.1665976

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