In vivo generated human CAR T cells eradicate tumor cells

Chimeric antigen receptor (CAR) T cells are in prime focus of current research in cancer immunotherapy. Facilitating CAR T cell generation is among the top goals. We have recently demonstrated direct in vivo generation of human CD19-CAR T cells by targeting CD8(+) cells using lentiviral vectors (LVs...

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Detalles Bibliográficos
Autores principales: Agarwal, Shiwani, Weidner, Tatjana, Thalheimer, Frederic B., Buchholz, Christian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844313/
https://www.ncbi.nlm.nih.gov/pubmed/31741773
http://dx.doi.org/10.1080/2162402X.2019.1671761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844313/
https://www.ncbi.nlm.nih.gov/pubmed/31741773
http://dx.doi.org/10.1080/2162402X.2019.1671761

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