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In vivo generated human CAR T cells eradicate tumor cells
Chimeric antigen receptor (CAR) T cells are in prime focus of current research in cancer immunotherapy. Facilitating CAR T cell generation is among the top goals. We have recently demonstrated direct in vivo generation of human CD19-CAR T cells by targeting CD8(+) cells using lentiviral vectors (LVs...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844313/ https://www.ncbi.nlm.nih.gov/pubmed/31741773 http://dx.doi.org/10.1080/2162402X.2019.1671761 |