T-cell-specific mTOR deletion in mice ameliorated CD4(+) T-cell survival in lethal sepsis induced by severe invasive candidiasis

The mammalian target of rapamycin (mTOR) pathway can mediate T-cell survival; however, the role of this pathway in T-cell survival during fungal sepsis is unclear. Here, we investigated the role of the mTOR pathway in CD4(+) T-cell survival in a mouse model of rapidly progressive lethal sepsis induc...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Bai, Guangxu, Cui, Na, Han, Wen, Long, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844314/
https://www.ncbi.nlm.nih.gov/pubmed/31668132
http://dx.doi.org/10.1080/21505594.2019.1685151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844314/
https://www.ncbi.nlm.nih.gov/pubmed/31668132
http://dx.doi.org/10.1080/21505594.2019.1685151

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