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Assessment of methods for serum extracellular vesicle small RNA sequencing to support biomarker development

Extracellular vesicles (EVs) have great potential as a source for clinically relevant biomarkers since they can be readily isolated from biofluids and carry microRNA (miRNA), mRNA, and proteins that can reflect disease status. However, the biological and technical variability of EV content is unknow...

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Detalles Bibliográficos
Autores principales: Srinivasan, Swetha, Duval, Manuel X., Kaimal, Vivek, Cuff, Carolyn, Clarke, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844434/
https://www.ncbi.nlm.nih.gov/pubmed/31741724
http://dx.doi.org/10.1080/20013078.2019.1684425