Cargando…
Blocking late stages of splicing quickly limits pre-spliceosome assembly in vivo
Pre-messenger RNA splicing involves multi-step assembly of the large spliceosome complexes that catalyse the two consecutive trans-esterification reactions, resulting in intron removal. There is evidence that proof-reading mechanisms monitor the fidelity of this complex process. Transcripts that fai...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844569/ https://www.ncbi.nlm.nih.gov/pubmed/31671032 http://dx.doi.org/10.1080/15476286.2019.1657788 |