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THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgeb...

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Autores principales: Alexander, Stephen PH, Mathie, Alistair, Peters, John A, Veale, Emma L, Striessnig, Jörg, Kelly, Eamonn, Armstrong, Jane F, Faccenda, Elena, Harding, Simon D, Pawson, Adam J, Sharman, Joanna L, Southan, Christopher, Davies, Jamie A, Aldrich, Richard W, Becirovic, Elvir, Biel, Martin, Catterall, William A, Conner, Alex C, Davies, Paul, Delling, Markus, Virgilio, Francesco Di, Falzoni, Simonetta, George, Chandy, Goldstein, Steve AN, Grissmer, Stephan, Ha, Kotdaji, Hammelmann, Verena, Hanukoglu, Israel, Jarvis, Mike, Jensen, Anders A, Kaczmarek, Leonard K, Kellenberger, Stephan, Kennedy, Charles, King, Brian, Lynch, Joseph W, Perez-Reyes, Edward, Plant, Leigh D, Rash, Lachlan D, Ren, Dejian, Sivilotti, Lucia G, Smart, Trevor G, Snutch, Terrance P, Tian, Jinbin, Van den Eynde, Charlotte, Vriens, Joris, Wei, Aguan D, Winn, Brenda T, Wulff, Heike, Xu, Haoxing, Yue, Lixia, Zhang, Xiaoli, Zhu, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844578/
https://www.ncbi.nlm.nih.gov/pubmed/31710715
http://dx.doi.org/10.1111/bph.14749
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author Alexander, Stephen PH
Mathie, Alistair
Peters, John A
Veale, Emma L
Striessnig, Jörg
Kelly, Eamonn
Armstrong, Jane F
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
Aldrich, Richard W
Becirovic, Elvir
Biel, Martin
Catterall, William A
Conner, Alex C
Davies, Paul
Delling, Markus
Virgilio, Francesco Di
Falzoni, Simonetta
George, Chandy
Goldstein, Steve AN
Grissmer, Stephan
Ha, Kotdaji
Hammelmann, Verena
Hanukoglu, Israel
Jarvis, Mike
Jensen, Anders A
Kaczmarek, Leonard K
Kellenberger, Stephan
Kennedy, Charles
King, Brian
Lynch, Joseph W
Perez-Reyes, Edward
Plant, Leigh D
Rash, Lachlan D
Ren, Dejian
Sivilotti, Lucia G
Smart, Trevor G
Snutch, Terrance P
Tian, Jinbin
Van den Eynde, Charlotte
Vriens, Joris
Wei, Aguan D
Winn, Brenda T
Wulff, Heike
Xu, Haoxing
Yue, Lixia
Zhang, Xiaoli
Zhu, Michael
author_facet Alexander, Stephen PH
Mathie, Alistair
Peters, John A
Veale, Emma L
Striessnig, Jörg
Kelly, Eamonn
Armstrong, Jane F
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
Aldrich, Richard W
Becirovic, Elvir
Biel, Martin
Catterall, William A
Conner, Alex C
Davies, Paul
Delling, Markus
Virgilio, Francesco Di
Falzoni, Simonetta
George, Chandy
Goldstein, Steve AN
Grissmer, Stephan
Ha, Kotdaji
Hammelmann, Verena
Hanukoglu, Israel
Jarvis, Mike
Jensen, Anders A
Kaczmarek, Leonard K
Kellenberger, Stephan
Kennedy, Charles
King, Brian
Lynch, Joseph W
Perez-Reyes, Edward
Plant, Leigh D
Rash, Lachlan D
Ren, Dejian
Sivilotti, Lucia G
Smart, Trevor G
Snutch, Terrance P
Tian, Jinbin
Van den Eynde, Charlotte
Vriens, Joris
Wei, Aguan D
Winn, Brenda T
Wulff, Heike
Xu, Haoxing
Yue, Lixia
Zhang, Xiaoli
Zhu, Michael
author_sort Alexander, Stephen PH
collection PubMed
description The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (http://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14749. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
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spelling pubmed-68445782019-11-22 THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels Alexander, Stephen PH Mathie, Alistair Peters, John A Veale, Emma L Striessnig, Jörg Kelly, Eamonn Armstrong, Jane F Faccenda, Elena Harding, Simon D Pawson, Adam J Sharman, Joanna L Southan, Christopher Davies, Jamie A Aldrich, Richard W Becirovic, Elvir Biel, Martin Catterall, William A Conner, Alex C Davies, Paul Delling, Markus Virgilio, Francesco Di Falzoni, Simonetta George, Chandy Goldstein, Steve AN Grissmer, Stephan Ha, Kotdaji Hammelmann, Verena Hanukoglu, Israel Jarvis, Mike Jensen, Anders A Kaczmarek, Leonard K Kellenberger, Stephan Kennedy, Charles King, Brian Lynch, Joseph W Perez-Reyes, Edward Plant, Leigh D Rash, Lachlan D Ren, Dejian Sivilotti, Lucia G Smart, Trevor G Snutch, Terrance P Tian, Jinbin Van den Eynde, Charlotte Vriens, Joris Wei, Aguan D Winn, Brenda T Wulff, Heike Xu, Haoxing Yue, Lixia Zhang, Xiaoli Zhu, Michael Br J Pharmacol The Concise Guide to Pharmacology 2019/20 The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (http://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point‐in‐time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14749. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein‐coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid‐2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC‐IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate. John Wiley and Sons Inc. 2019-11-11 2019-12 /pmc/articles/PMC6844578/ /pubmed/31710715 http://dx.doi.org/10.1111/bph.14749 Text en © 2019 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle The Concise Guide to Pharmacology 2019/20
Alexander, Stephen PH
Mathie, Alistair
Peters, John A
Veale, Emma L
Striessnig, Jörg
Kelly, Eamonn
Armstrong, Jane F
Faccenda, Elena
Harding, Simon D
Pawson, Adam J
Sharman, Joanna L
Southan, Christopher
Davies, Jamie A
Aldrich, Richard W
Becirovic, Elvir
Biel, Martin
Catterall, William A
Conner, Alex C
Davies, Paul
Delling, Markus
Virgilio, Francesco Di
Falzoni, Simonetta
George, Chandy
Goldstein, Steve AN
Grissmer, Stephan
Ha, Kotdaji
Hammelmann, Verena
Hanukoglu, Israel
Jarvis, Mike
Jensen, Anders A
Kaczmarek, Leonard K
Kellenberger, Stephan
Kennedy, Charles
King, Brian
Lynch, Joseph W
Perez-Reyes, Edward
Plant, Leigh D
Rash, Lachlan D
Ren, Dejian
Sivilotti, Lucia G
Smart, Trevor G
Snutch, Terrance P
Tian, Jinbin
Van den Eynde, Charlotte
Vriens, Joris
Wei, Aguan D
Winn, Brenda T
Wulff, Heike
Xu, Haoxing
Yue, Lixia
Zhang, Xiaoli
Zhu, Michael
THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title_full THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title_fullStr THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title_full_unstemmed THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title_short THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels
title_sort concise guide to pharmacology 2019/20: ion channels
topic The Concise Guide to Pharmacology 2019/20
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844578/
https://www.ncbi.nlm.nih.gov/pubmed/31710715
http://dx.doi.org/10.1111/bph.14749
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