Cargando…
Novel Role of Lck in Leptin-Induced Inflammation and Implications for Renal Aging
Aging is associated with increased fat mass and elevated serum leptin levels (hyperleptinemia), causing proinflammation in the kidneys where it plays a primary role in the removal of endogenous leptin from the circulation. Lymphocyte-specific kinase (Lck) is a positive regulator of inflammatory sign...
Autores principales: | Kim, Dae Hyun, Park, June Whoun, Jeong, Hyoung Oh, Lee, Bonggi, Chung, Ki Wung, Lee, Yujeong, Jung, Hee Jin, Hyun, Min Kyung, Lee, A Kyoung, Kim, Byeong Moo, Yu, Byung Pal, Chung, Hae Young |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844581/ https://www.ncbi.nlm.nih.gov/pubmed/31788330 http://dx.doi.org/10.14336/AD.2019.0218 |
Ejemplares similares
-
MMP2-A2M interaction increases ECM accumulation in aged rat kidney and its modulation by calorie restriction
por: Kim, Kyung Mok, et al.
Publicado: (2017) -
Involvement of NF-κBIZ and related cytokines in age-associated renal fibrosis
por: Chung, Ki Wung, et al.
Publicado: (2017) -
β-Hydroxybutyrate Suppresses Lipid Accumulation in Aged Liver through GPR109A-mediated Signaling
por: Lee, A Kyoung, et al.
Publicado: (2020) -
Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation
por: Kim, Dae Hyun, et al.
Publicado: (2020) -
Small RNAs induce the activation of the pro‐inflammatory TLR7 signaling pathway in aged rat kidney
por: Lee, Eun Kyeong, et al.
Publicado: (2017)