Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application

Exosome, is identified as a nature nanocarrier and intercellular messenger that regulates cell to cell communication. Autophagy is critical in maintenance of protein homeostasis by degradation of damaged proteins and organelles. Autophagy and exosomes take pivotal roles in cellular homeostasis and c...

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Detalles Bibliográficos
Autores principales: Tian, Jinfan, Popal, Mohammad Sharif, Zhao, Yingke, Liu, Yanfei, Chen, Keji, Liu, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JKL International LLC 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844582/
https://www.ncbi.nlm.nih.gov/pubmed/31788341
http://dx.doi.org/10.14336/AD.2018.1020
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author Tian, Jinfan
Popal, Mohammad Sharif
Zhao, Yingke
Liu, Yanfei
Chen, Keji
Liu, Yue
author_facet Tian, Jinfan
Popal, Mohammad Sharif
Zhao, Yingke
Liu, Yanfei
Chen, Keji
Liu, Yue
author_sort Tian, Jinfan
collection PubMed
description Exosome, is identified as a nature nanocarrier and intercellular messenger that regulates cell to cell communication. Autophagy is critical in maintenance of protein homeostasis by degradation of damaged proteins and organelles. Autophagy and exosomes take pivotal roles in cellular homeostasis and cardiovascular disease. Currently, the coordinated mechanisms for exosomes and autophagy in the maintenance of cellular fitness are now garnering much attention. In the present review, we discussed the interplay of exosomes and autophagy in the context of physiology and pathology of the heart, which might provide novel insights for diagnostic and therapeutic application of cardiovascular diseases.
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spelling pubmed-68445822019-12-01 Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application Tian, Jinfan Popal, Mohammad Sharif Zhao, Yingke Liu, Yanfei Chen, Keji Liu, Yue Aging Dis Review Exosome, is identified as a nature nanocarrier and intercellular messenger that regulates cell to cell communication. Autophagy is critical in maintenance of protein homeostasis by degradation of damaged proteins and organelles. Autophagy and exosomes take pivotal roles in cellular homeostasis and cardiovascular disease. Currently, the coordinated mechanisms for exosomes and autophagy in the maintenance of cellular fitness are now garnering much attention. In the present review, we discussed the interplay of exosomes and autophagy in the context of physiology and pathology of the heart, which might provide novel insights for diagnostic and therapeutic application of cardiovascular diseases. JKL International LLC 2019-12-01 /pmc/articles/PMC6844582/ /pubmed/31788341 http://dx.doi.org/10.14336/AD.2018.1020 Text en Copyright: © 2019 Tian et al. http://creativecommons.org/licenses/by/2.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.
spellingShingle Review
Tian, Jinfan
Popal, Mohammad Sharif
Zhao, Yingke
Liu, Yanfei
Chen, Keji
Liu, Yue
Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title_full Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title_fullStr Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title_full_unstemmed Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title_short Interplay between Exosomes and Autophagy in Cardiovascular Diseases: Novel Promising Target for Diagnostic and Therapeutic Application
title_sort interplay between exosomes and autophagy in cardiovascular diseases: novel promising target for diagnostic and therapeutic application
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844582/
https://www.ncbi.nlm.nih.gov/pubmed/31788341
http://dx.doi.org/10.14336/AD.2018.1020
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