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The Long-lasting Radioprotective Effect of Caffeic Acid in Mice Exposed to Total Body Irradiation by Modulating Reactive Oxygen Species Generation and Hematopoietic Stem Cell Senescence-Accompanied Long-term Residual Bone Marrow Injury
Total body irradiation (TBI) serves as an effectively curative therapy for cancer patients and adversely causes long-term residual bone marrow (BM) injury with premature senescence of hematopoietic stem cells (HSCs), which is mediated by increased production of reactive oxygen species (ROS). In the...
Autores principales: | Sim, Hyun-Jaung, Bhattarai, Govinda, Lee, Joshua, Lee, Jeong-Chae, Kook, Sung-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
JKL International LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844585/ https://www.ncbi.nlm.nih.gov/pubmed/31788343 http://dx.doi.org/10.14336/AD.2019.0208 |
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