Cargando…
Targeting Microglial and Neuronal Toll-like Receptor 2 in Synucleinopathies
Synucleinopathies are neurodegenerative disorders characterized by the progressive accumulation of α-synuclein (α-syn) in neurons and glia and include Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). In this review, we consolidate our key findings and recent studies concerning the role...
Autores principales: | Kwon, Somin, Iba, Michiyo, Masliah, Eliezer, Kim, Changyoun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society for Brain and Neural Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844834/ https://www.ncbi.nlm.nih.gov/pubmed/31698547 http://dx.doi.org/10.5607/en.2019.28.5.547 |
Ejemplares similares
-
Immunotherapies for Aging-Related Neurodegenerative Diseases—Emerging Perspectives and New Targets
por: Kwon, Somin, et al.
Publicado: (2020) -
Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation
por: Kim, Changyoun, et al.
Publicado: (2018) -
Non-cell-autonomous Neurotoxicity of α-synuclein Through Microglial Toll-like Receptor 2
por: Kim, Changyoun, et al.
Publicado: (2016) -
Does SARS-CoV-2 affect neurodegenerative disorders? TLR2, a potential receptor for SARS-CoV-2 in the CNS
por: Szabo, Marcell P., et al.
Publicado: (2022) -
Role of Alterations in Protein Kinase p38γ in the Pathogenesis of the Synaptic Pathology in Dementia With Lewy Bodies and α-Synuclein Transgenic Models
por: Iba, Michiyo, et al.
Publicado: (2020)