Cargando…

3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABA(A)-benzodiazepine Receptors

3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. It has been reported that, in addition to its known properties as a phytoncide, 3-carene has anti-inflammatory, antimicrobial, and anxiolytic effects. We have previously demonstrated that α-pinene, the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Woo, Junsung, Yang, Hyejin, Yoon, Minseok, Gadhe, Changdev G., Pae, Ae Nim, Cho, Suengmok, Lee, C. Justin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society for Brain and Neural Sciences 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844839/ https://www.ncbi.nlm.nih.gov/pubmed/31698551 http://dx.doi.org/10.5607/en.2019.28.5.593

Ejemplares similares

Investigation of Molecular Details of Keap1-Nrf2 Inhibitors Using Molecular Dynamics and Umbrella Sampling Techniques
por: Londhe, Ashwini Machhindra, et al.
Publicado: (2019)

Glutamate Permeability of Chicken Best1
por: Lee, Jung Moo, et al.
Publicado: (2022)

Sleep-enhancing Effects of Phytoncide Via Behavioral, Electrophysiological, and Molecular Modeling Approaches
por: Woo, Junsung, et al.
Publicado: (2020)

Dieckol, a Major Marine Polyphenol, Enhances Non-Rapid Eye Movement Sleep in Mice via the GABA(A)-Benzodiazepine Receptor
por: Yoon, Minseok, et al.
Publicado: (2020)

Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent
por: Shin, Seulgi, et al.
Publicado: (2019)

Biotransformation of (1S)-2-Carene and (1S)-3-Carene by Picea abies Suspension Culture
por: Dvorakova, Marcela, et al.
Publicado: (2011)

Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy
por: Kim, Byung-Hak, et al.
Publicado: (2019)

The influence of phytoncides on the immune system of broiler chickens and turkeys
por: Koncicki, Andrzej, et al.
Publicado: (2015)

Anti-Inflammatory Effect of Phytoncide in an Animal Model of Gastrointestinal Inflammation
por: Memon, Azra, et al.
Publicado: (2021)

Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain
por: Yang, Hak Kyun, et al.
Publicado: (2018)

Phytoncides in The Prevention and Therapy of Blackhead Disease and Their Effect on The Turkey Immune System
por: Tykałowski, Bartłomiej, et al.
Publicado: (2021)

Structural Insights from Binding Poses of CCR2 and CCR5 with Clinically Important Antagonists: A Combined In Silico Study
por: Kothandan, Gugan, et al.
Publicado: (2012)

Effect of 3-Carene and the Micellar Formulation on Leishmania (Leishmania) amazonensis
por: Silva, Audrey Rouse Soares Tavares, et al.
Publicado: (2023)

Benzodiazepine Modulation of GABA(A) Receptors: A Mechanistic Perspective
por: Goldschen-Ohm, Marcel P.
Publicado: (2022)

Dietary Phytoncide Supplementation Improved Growth Performance and Meat Quality of Finishing Pigs
por: Li, Han Lin, et al.
Publicado: (2016)

GABA(A) receptor subtypes and benzodiazepine use, misuse, and abuse
por: Engin, Elif
Publicado: (2023)

Improvement of Milk Fatty Acid Composition for Production of Functional Milk by Dietary Phytoncide Oil Extracted from Discarded Pine Nut Cones (Pinus koraiensis) in Holstein Dairy Cows
por: Kim, Min Jeong, et al.
Publicado: (2016)

Pathways to Highly Oxidized Products in the Δ3-Carene + OH System
por: D’Ambro, Emma L., et al.
Publicado: (2022)

Synthesis of Bioactive Compounds from 3-Carene (II): Synthesis, Antifungal Activity and 3D-QSAR Study of (Z)- and (E)-3-Caren-5-One Oxime Sulfonates
por: Kang, Guo-Qiang, et al.
Publicado: (2019)

Benzodiazepines modulate GABA(A )receptors by reducing a gamma-subunit-mediated inhibition of GABA sensitivity
por: Baburin, Igor, et al.
Publicado: (2009)

Gastroprotective effect of phytoncide extract from Pinus koraiensis pinecone in Helicobacter pylori infection
por: Kim, Se-eun, et al.
Publicado: (2020)

Isoliquiritigenin, a Chalcone Compound, Enhances Spontaneous Inhibitory Postsynaptic Response
por: Woo, Junsung, et al.
Publicado: (2014)

Context Dependent Benzodiazepine Modulation of GABA(A) Receptor Opening Frequency
por: Bianchi, Matt T
Publicado: (2010)

Different Benzodiazepines Bind with Distinct Binding Modes to GABA(A) Receptors
por: Elgarf, Alshaimaa A., et al.
Publicado: (2018)

Synthesis and Antifungal Activity of Novel 3-Caren-5-One Oxime Esters
por: Huang, Min, et al.
Publicado: (2017)

In Silico Quantitative Structure-Activity Relationship Studies on P-gp Modulators of Tetrahydroisoquinoline-Ethyl-Phenylamine Series
por: Gadhe, Changdev G, et al.
Publicado: (2011)

Effects of phytoncide on immune cells and psychological stress of gynecological cancer survivors: randomized controlled trials
por: Heo, Seung-Jae, et al.
Publicado: (2023)

Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABA(A) receptor subtype
por: Ralvenius, William T., et al.
Publicado: (2015)

Influence of GABA(A) Receptor α Subunit Isoforms on the Benzodiazepine Binding Site
por: Lüscher, Benjamin P., et al.
Publicado: (2012)

Flumazenil-Insensitive Benzodiazepine Effects in Recombinant αβ and Neuronal GABA(A) Receptors
por: Lian, Jing-Jing, et al.
Publicado: (2020)

The blood-to-plasma ratio and predicted GABA(A)-binding affinity of designer benzodiazepines
por: Manchester, Kieran R., et al.
Publicado: (2022)

Novel Dental Poly (Methyl Methacrylate) Containing Phytoncide for Antifungal Effect and Inhibition of Oral Multispecies Biofilm
por: Lee, Myung-Jin, et al.
Publicado: (2020)

A Unified Model of the GABA(A) Receptor Comprising Agonist and Benzodiazepine Binding Sites
por: Bergmann, Rikke, et al.
Publicado: (2013)

A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model
por: Clayton, Terry, et al.
Publicado: (2015)

Curcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines
por: Liu, Yan-Mei, et al.
Publicado: (2017)

Comparison of walking overground and in a Computer Assisted Rehabilitation Environment (CAREN) in individuals with and without transtibial amputation
por: Gates, Deanna H, et al.
Publicado: (2012)

Triphlorethol A, a Dietary Polyphenol from Seaweed, Decreases Sleep Latency and Increases Non-Rapid Eye Movement Sleep in Mice
por: Yoon, Minseok, et al.
Publicado: (2018)

Antimicrobial Activity and Proposed Action Mechanism of 3-Carene against Brochothrix thermosphacta and Pseudomonas fluorescens
por: Shu, Huizhen, et al.
Publicado: (2019)

Evaluation of the Insecticidal Activities of α-Pinene and 3-Carene on Sitophilus zeamais Motschulsky (Coleoptera: Curculionidae)
por: Langsi, Jacob D., et al.
Publicado: (2020)

In Vitro Evaluation of Antiprotozoal Properties, Cytotoxicity Effect and Anticancer Activity of New Essential-Oil Based Phytoncide Mixtures
por: Iwiński, Hubert, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5u56ad6gh808cp3pleqlo39sh9