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INCREASED HSP25 DRIVES THE TRANSITION FROM PROTEASOME TO AUTOPHAGY-MEDIATED DEGRADATION UNDER PROTEOTOXIC STRESS
Accumulation of protein aggregates are a common pathology in many neurodegenerative disorders. This accumulation may be due to a function decline in the protein homeostasis network known to occur during the aging process. Small heat shock proteins are a class of molecular chaperones that assist in p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844961/ http://dx.doi.org/10.1093/geroni/igz038.371 |