THE LONGEVITY ASSOCIATED ALLELE OF FOXO3 PROTECTS AGAINST TELOMERE ATTRITION DURING AGING

Telomere attrition in proliferative tissues is a hallmark feature of human aging. To date, the genetic influence on the rate of telomere attrition is poorly understood. Previously we discovered a variant of the FOXO3 gene that is strongly associated with human longevity, an observation that has been...

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Detalles Bibliográficos
Autores principales: Allsopp, Richard, Davy, Philip, Willcox, Craig, Chen, Randi, Shimabukuro, Michio, de Vivo, Immaculata, Willcox, Bradley J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Session 830 (Poster)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6845095/
http://dx.doi.org/10.1093/geroni/igz038.374

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